Stösslein F, Schwenke A, Münster W, Köhler H, Mebel M, Raatzsch H, Steude U, Krosegk G
Bereich Medizin Charité, Kreiskrankenhaus Pasewalk, Urologische Abteilung.
Z Urol Nephrol. 1987 Oct;80(10):577-86.
In a retrospective study of 303 patients with renal cell carcinomas the prognostic influence of the percutaneous transvasal embolization of the renal artery was demonstrated. In form of the life-table-method we compared statistically the survival rates of preoperatively or palliatively embolized patients with such ones who were only nephrectomized or treated only symptomatically. In the tumour stages T2 and T3 the preoperative percutaneous transvasal embolization leads to a clearly higher survival rate; in stage T2 statistically significant. After palliative embolization the improvement of the prognosis is evident compared with the inoperable patients who were treated only symptomatically. The prognosis after palliative preoperative percutaneous transvasal embolization and retarded nephrectomy is not worse than after preoperative percutaneous transvasal embolization and immediate nephrectomy. The effect of the preoperative and palliative embolization improving the prognosis should incite all partners who up to now objected to this therapeutic method to reconsider their therapy concept.
在一项对303例肾细胞癌患者的回顾性研究中,证实了经皮经血管肾动脉栓塞术的预后影响。我们采用寿命表法,对术前或姑息性栓塞患者与仅接受肾切除术或仅进行对症治疗患者的生存率进行了统计学比较。在肿瘤分期为T2和T3时,术前经皮经血管栓塞术可显著提高生存率;在T2期具有统计学意义。与仅接受对症治疗的不可手术患者相比,姑息性栓塞术后预后明显改善。姑息性术前经皮经血管栓塞术联合延迟肾切除术的预后并不比术前经皮经血管栓塞术联合即刻肾切除术差。术前和姑息性栓塞术改善预后的效果应促使所有至今反对这种治疗方法的各方重新考虑其治疗理念。