与颈椎退行性椎间盘疾病相关的合并症。
Comorbidities associated with cervical spine degenerative disc disease.
作者信息
Lambrechts Mark J, Maryan Kyle, Whitman Wyatt, Yen Tzu-Chuan, Li Jinpu, Leary Emily V, Cook James L, Choma Theodore J
机构信息
Department of Orthopaedic Surgery, University of Missouri, Columbia, MO, USA.
University of Missouri School of Medicine, Columbia, MO, USA.
出版信息
J Orthop. 2021 Jul 16;26:98-102. doi: 10.1016/j.jor.2021.07.008. eCollection 2021 Jul-Aug.
Determining important links between medical comorbidities and cervical spine degenerative disc disease (DDD) will help elucidate pathomechanisms of disc degeneration. Electronic medical records and magnetic resonance imaging were retrospectively reviewed to evaluate 799 patients assessed for cervical spine pathology. Bivariate analysis identified older age, diabetes, ASA class, cancer, COPD, depression, hypertension, hypothyroidism, Medicare status, peripheral vascular disease, history of previous cervical spine surgery, smoking, and lower median household income as having strong associations with increased cumulative grade of cervical spine DDD. This study provides evidence suggesting aging and accumulation of medical comorbidities influence severity of cervical spine DDD.
确定医学合并症与颈椎退行性椎间盘疾病（DDD）之间的重要联系将有助于阐明椎间盘退变的发病机制。对电子病历和磁共振成像进行回顾性分析，以评估799例接受颈椎病理检查的患者。双变量分析确定年龄较大、糖尿病、美国麻醉医师协会（ASA）分级、癌症、慢性阻塞性肺疾病（COPD）、抑郁症、高血压、甲状腺功能减退、医疗保险状态、外周血管疾病、既往颈椎手术史、吸烟以及较低的家庭收入中位数与颈椎DDD累积分级增加密切相关。本研究提供的证据表明，衰老和医学合并症的积累会影响颈椎DDD的严重程度。
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