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中国住院 2 型糖尿病患者的心血管危险因素状况。

Cardiovascular Risk Factor Status in Hospitalized Patients With Type 2 Diabetes in China.

机构信息

Department of Endocrinology and Metabolism, Tianjin Medical University General Hospital, Tianjin, China.

Pennington Biomedical Research Center, Baton Rouge, LA, United States.

出版信息

Front Endocrinol (Lausanne). 2021 Jul 22;12:664183. doi: 10.3389/fendo.2021.664183. eCollection 2021.

Abstract

BACKGROUND

Controlling blood glucose, blood pressure, and blood lipid is of great importance for patients with type 2 diabetes, not only for cardiovascular disease, but also for other complications. Previous studies mainly focused on the control rate of outpatients, and the results were suboptimal, but few studies aimed at the inpatients.

METHOD

The present study involved 3,245 hospitalized patients with type 2 diabetes from 2013 to 2017 in the Department of Endocrinology and Metabolism of Tianjin Medical University General Hospital. The percentages of inpatients who attained the goals of the China Diabetes Society and the American Diabetes Association were calculated for major cardiovascular risk factors (HbA1c, blood pressure, and blood lipid). The prevalence of microvascular and macrovascular complications was also assessed.

RESULT

The percentages of patients who met the Chinese Diabetes Society goals-HbA1c <7%, blood pressure <130/80 mmHg, normal lipids, and all three goals-were 26.7, 14.8, 10.4, and 0.2% in 2013 and 30.5, 16.2, 8.0, and 0.9% in 2017, respectively. The percentage of patients who met all three American Diabetes Association goals (HbA1c<7%, blood pressure <140/90 mmHg, low-density lipoprotein cholesterol <2.6 mmol/L) increased from 4.3% in 2013 to 9.0% in 2017. The prevalence of major diabetes complications including coronary heart disease (31.7 . 31.9%), stroke (16.7 . 14.8%), diabetic kidney disease (37.9 . 35.8%), diabetic retinopathy (48.0 . 46.5%), neuropathy (63.1 . 61.9%), and diabetic foot (0.8 . 1.2%) were stable from 2013 to 2017.

CONCLUSION

During 2013 to 2017, control rates of major cardiovascular risk factors including HbA1c, blood pressure, and low-density lipoprotein cholesterol were improved among hospitalized patients in Tianjin, China.

摘要

背景

对于 2 型糖尿病患者,控制血糖、血压和血脂水平非常重要,这不仅对心血管疾病有影响,对其他并发症也有影响。先前的研究主要集中在门诊患者的控制率上,结果并不理想,但很少有研究针对住院患者。

方法

本研究纳入了 2013 年至 2017 年期间天津医科大学总医院内分泌代谢科的 3245 例住院 2 型糖尿病患者。计算了达到中国糖尿病学会和美国糖尿病协会目标的主要心血管危险因素(HbA1c、血压和血脂)的住院患者百分比。还评估了微血管和大血管并发症的患病率。

结果

2013 年,HbA1c<7%、血压<130/80mmHg、血脂正常和三项均达标的患者比例分别为 26.7%、14.8%、10.4%和 0.2%;2017 年,相应比例分别为 30.5%、16.2%、8.0%和 0.9%。同时达到美国糖尿病协会三项目标(HbA1c<7%、血压<140/90mmHg、低密度脂蛋白胆固醇<2.6mmol/L)的患者比例从 2013 年的 4.3%增加到 2017 年的 9.0%。包括冠心病(31.7%、31.9%)、脑卒中(16.7%、14.8%)、糖尿病肾病(37.9%、35.8%)、糖尿病视网膜病变(48.0%、46.5%)、神经病变(63.1%、61.9%)和糖尿病足(0.8%、1.2%)在内的主要糖尿病并发症的患病率从 2013 年到 2017 年保持稳定。

结论

2013 年至 2017 年期间,中国天津住院 2 型糖尿病患者的主要心血管危险因素(HbA1c、血压和低密度脂蛋白胆固醇)控制率得到改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c41c/8339370/c38af92f2953/fendo-12-664183-g001.jpg

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