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两例伴有肾静脉血栓形成的血管炎

Two Cases of Vasculitis with Renal Vein Thrombosis.

作者信息

Mazumdar Mehul, Mandowara Bhavin S, Patel Himanshu A, Darji Prakash

机构信息

Department of Nephrology and Renal Transplant, Zydus Hospital, Ahmedabad, Gujarat, India.

出版信息

Indian J Nephrol. 2021 May-Jun;31(3):283-285. doi: 10.4103/ijn.IJN_306_19. Epub 2021 Feb 8.

Abstract

We present a series of two cases of ANCA associated Vasculitis (AAV) presenting as Pulmonary Renal syndrome with associated renal vein thrombosis. Although there are enough evidences suggesting association of venous thrombosis with AAVs, the incidence of renal vein thrombosis is rare. Renal vein thrombosis should be ruled out in cases where there is delay in recovery of renal function in patients with AAV. Positive laboratory values for anti-Proteinase-3 (PR3) and anti-Myeloperoxidase (MPO) ANCA in the cases that presented as Rapidly Progressive Glomerulonephritis, helped in early initiation of treatment with complete recovery of Renal function.

摘要

我们报告了两例抗中性粒细胞胞浆抗体相关性血管炎(AAV),表现为肺肾综合征并伴有肾静脉血栓形成。尽管有足够证据表明静脉血栓形成与AAV相关,但肾静脉血栓形成的发生率很低。对于AAV患者,如果肾功能恢复延迟,应排除肾静脉血栓形成。在表现为快速进展性肾小球肾炎的病例中,抗蛋白酶3(PR3)和抗髓过氧化物酶(MPO)抗中性粒细胞胞浆抗体的实验室检查结果呈阳性,有助于早期开始治疗并使肾功能完全恢复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6aea/8330659/f952e5306cfc/IJN-31-283-g001.jpg

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