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腹腔镜袖状胃切除术对2型糖尿病患者血糖控制的影响

The Effect of Laparoscopic Sleeve Gastrectomy on Glycemic Control in Type 2 Diabetic Patients.

作者信息

Al Khayat Ali, Al Hendi Sarah, Qadhi Iman, Al Murad Ahmad

机构信息

General Surgery, Mubarak Al-Kabeer University Hospital, Kuwait City, KWT.

Family Medicine, Al-Surrah Clinic, Al-Asimah Health Center, Kuwait City, KWT.

出版信息

Cureus. 2021 Aug 7;13(8):e16986. doi: 10.7759/cureus.16986. eCollection 2021 Aug.

DOI:10.7759/cureus.16986
PMID:34377616
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8349304/
Abstract

Introduction The prevalence of diabetes mellitus type II (T2DM) in Kuwait in 2013 was 23.09%, ranking ninth globally and second in the Middle East and North Africa (MENA) region. It's been frequently reported as a growing public health concern. Our retrospective study will focus on the effect of laparoscopic sleeve gastrectomy (LSG) on the glycemic control of T2DM. Methods From December 2012 to January 2014, 70 patients with T2DM underwent LSG during the study period. A retrospective patient file review was performed and a follow-up on participants was carried out in February 2014. Fasting plasma glucose (FPG) was taken pre- and post-operatively. Patients were followed up to monitor the change in diabetic medications in terms of quantity, type and dose. Results The mean reduction of FPG after surgery was 2.94+3.66 (P < 0.001) over a mean interval of eight days (range, 0-34 days). Immediate reduction in FPG was seen in 61 patients (87%), and the greatest reduction was seen in the age group <40 years. Diabetes remission was seen in 49 patients (70%), while 20 (29%) had reduction in medication. All patients underwent a safe surgical procedure. There were no conversions to open surgery and no significant complications or mortalities. Conclusions Our study shows that LSG procedure has an immediate positive effect on the glycemic control of T2DM, in addition to the long-term evidence of complete resolution of diabetes in most patients or improvement in glycemic control, which has further highlighted the positive outcome of LSG, diminishing morbidity, risk factors, co-morbidities and health-expenditure.

摘要

引言 2013年科威特II型糖尿病(T2DM)的患病率为23.09%,在全球排名第九,在中东和北非(MENA)地区排名第二。它经常被报道为一个日益严重的公共卫生问题。我们的回顾性研究将聚焦于腹腔镜袖状胃切除术(LSG)对T2DM血糖控制的影响。

方法 2012年12月至2014年1月,70例T2DM患者在研究期间接受了LSG。进行了回顾性患者档案审查,并于2014年2月对参与者进行了随访。术前和术后均采集空腹血糖(FPG)。对患者进行随访,以监测糖尿病药物在数量、类型和剂量方面的变化。

结果 术后FPG平均降低2.94 + 3.66(P < 0.001),平均间隔8天(范围0 - 34天)。61例患者(87%)FPG立即降低,年龄<40岁组降低幅度最大。49例患者(70%)糖尿病缓解,20例(29%)药物用量减少。所有患者均接受了安全的手术。没有转为开放手术的情况,也没有严重并发症或死亡病例。

结论 我们

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