热量限制会使微生物组为致病菌做好准备吗？
Does caloric restriction prime the microbiome for pathogenic bacteria?
机构信息
Human Science and Design, Robbins College of Health and Human Sciences, Baylor University, Waco, TX, USA.
Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA.
出版信息
Cell Host Microbe. 2021 Aug 11;29(8):1209-1211. doi: 10.1016/j.chom.2021.07.009.
PMID:34384521
Abstract
A recent study in Nature finds significant shifts in the gut microbiome of post-menopausal women on severe calorie restriction concomitant with weight loss. Microbiota transplantation to germ-free mice display a similar weight loss, along with a bloom in C. difficile, unlocking clues to microbial metabolic alteration in weight loss.
摘要
最近发表在《自然》杂志上的一项研究发现，严格限制卡路里摄入并随之减轻体重的绝经后妇女的肠道微生物组发生了显著变化。将这些微生物组移植到无菌小鼠身上，可使它们体重减轻，同时艰难梭菌大量繁殖，这为研究体重减轻过程中微生物代谢的改变提供了线索。
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