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慢性肾脏病合并妊娠中的贫血

Anaemia in chronic kidney disease pregnancy.

作者信息

Morton Adam, Burke Michael, Morton Anthony, Kumar Sailesh

机构信息

Mater Health and University of QLD, QLD, Australia.

Infectious Diseases, Metro South Health, QLD, Australia.

出版信息

Obstet Med. 2021 Jun;14(2):116-120. doi: 10.1177/1753495X20948985. Epub 2020 Sep 1.

Abstract

AIM

To review the incidence and management of anaemia and outcomes in pregnancies in a cohort of Australian women with chronic kidney disease.

METHODS

A retrospective audit of 63 pregnancies in 52 women with chronic kidney disease.

RESULTS

Sixty-eight percent of chronic kidney disease pregnancies were complicated by haemoglobin less than 100 g/L. Iron stores were measured in only 62% of all pregnancies. Serum ferritin was less than 100 ng/ml in 95% of those tested. Erythropoietin-stimulating agents were used in 24 pregnancies (38%). Intravenous iron was used in only nine non-dialysis pregnancies.

CONCLUSION

Greater awareness of the importance of regular measurement of iron stores and appropriate levels for repletion in chronic kidney disease pregnancies amongst health professionals involved in obstetric care may result in earlier detection and treatment of iron deficiency, and potentially improve maternal and fetal outcomes.

摘要

目的

回顾澳大利亚慢性肾脏病女性队列中妊娠期间贫血的发生率、管理及结局。

方法

对52例慢性肾脏病女性的63次妊娠进行回顾性审计。

结果

68%的慢性肾脏病妊娠合并血红蛋白低于100g/L。仅62%的妊娠测量了铁储备。在所有接受检测的孕妇中,95%的血清铁蛋白低于100ng/ml。24次妊娠(38%)使用了促红细胞生成素。仅9例非透析妊娠使用了静脉铁剂。

结论

参与产科护理的医护人员若能更清楚地认识到在慢性肾脏病妊娠中定期测量铁储备及补充合适水平铁的重要性,可能会更早发现和治疗缺铁,并有可能改善母婴结局。

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