耳蜗神经和面神经的儿茶酚胺含量。正常小鼠和突变小鼠的高效液相色谱分析。

Catecholamine content of cochlear and facial nerves. High-performance liquid chromatography analyses in normal and mutant mice.

作者信息

Anniko M, Pequignot J M

机构信息

Department of Otolaryngology and Head & Neck Surgery and Medicine, Umeá University Hospital, Sweden.

出版信息

Arch Otorhinolaryngol. 1987;244(5):262-4. doi: 10.1007/BF00468632.

DOI:10.1007/BF00468632

PMID:3439913

Abstract

The catecholamine content in cochlear and facial nerves was determined using high-performance liquid chromatography coupled with electro-chemical detection. Minute amounts of norepinephrine were detected in both nerves in normal CBA/CBA mice and homozygotic jerker mouse mutants, whereas norepinephrine was found only in the facial nerve in the dancer heterozygotic mouse mutant. Dopamine and epinephrine were not detected in any of the mouse strains.

摘要

采用高效液相色谱-电化学检测法测定耳蜗神经和面神经中的儿茶酚胺含量。在正常CBA/CBA小鼠和纯合子震颤小鼠突变体的两条神经中均检测到微量去甲肾上腺素，而在舞者杂合子小鼠突变体中仅在面神经中发现去甲肾上腺素。在任何小鼠品系中均未检测到多巴胺和肾上腺素。