Department of Ophthalmology, N.S.C.B. Subharti Medical College and Chhatrapati Shivaji Subharti Hospital, Meerut, Uttar Pradesh, India.
Department of Ophthalmology, All India Institute of Medical Sciences, Patna, India.
Indian J Ophthalmol. 2021 Sep;69(9):2401-2405. doi: 10.4103/ijo.IJO_2747_20.
To identify the exact time point during after following pterygium excision with a modified technique of sutureless, glueless limbal-conjunctival autograft, when stabilization of the change in corneal curvature is achieved; correlate size of pterygium with uncorrected visual acuity and astigmatism at baseline, and assess changes in these parameters postoperatively over time.
This prospective study longitudinally assessed 30 eyes of 30 north Indian adults with primary pterygium encroaching upon ≥1 mm of the cornea pre- and postoperatively at 1 week and then monthly for 4 months, recording uncorrected (UCVA) and best-corrected logMAR visual acuity, astigmatism and keratometry. Results were analyzed using ANOVA, Mauchly's test of sphericity with Greenhouse-Geisser correction, and post-hoc test using Bonferroni correction. Pearson's correlation coefficient r > 0.5 was considered clinically significant, and P < 0.05 statistically significant.
Pterygium size was well correlated with pre-operative astigmatism (r = 0.867, P < 0.001) and pre-operative UCVA (r = 0.856, P < 0.001). There was mean improvement of 0.43 logMAR units of visual acuity (P < 0.00001), a mean increase of 0.79D of keratometric value for the flatter meridian (P < 0.00001) and a mean reduction of 2.00D of astigmatism (P < 0.00001). At 2-month follow-up, the keratometric value for the flatter meridian approached the final keratometric reading at 4 months such that the difference was not significant (t = 1.185, P = 0.245). There were no significant complications or recurrence during the follow-up period.
Pterygium excision with modified autograft reduced corneal astigmatism and improved visual acuity comparable to classical technique. Alteration in corneal curvature stabilizes 2 months after surgery, when spectacle correction can be given to patients.
确定在进行改良的无缝线、无胶缘结角膜自体移植物翼状胬肉切除术后,角膜曲率变化稳定的确切时间点;将翼状胬肉的大小与术前未矫正视力和散光相关联,并评估术后随时间的这些参数的变化。
本前瞻性研究对 30 名印度北部成年人的 30 只眼进行了纵向评估,这些患者的原发性翼状胬肉侵犯角膜≥1 毫米,术前和术后 1 周,然后每月进行 4 个月,记录未矫正(UCVA)和最佳矫正对数视力、散光和角膜曲率。结果使用方差分析、Mauchly 球形检验和 Bonferroni 校正后的事后检验进行分析。Pearson 相关系数 r > 0.5 被认为具有临床意义,P < 0.05 具有统计学意义。
翼状胬肉大小与术前散光(r = 0.867,P < 0.001)和术前 UCVA(r = 0.856,P < 0.001)密切相关。视力平均提高 0.43 对数视力单位(P < 0.00001),较平坦子午线的角膜曲率值平均增加 0.79D(P < 0.00001),散光平均减少 2.00D(P < 0.00001)。在 2 个月的随访中,较平坦子午线的角膜曲率值接近 4 个月时的最终角膜曲率读数,差异无统计学意义(t = 1.185,P = 0.245)。在随访期间没有发生明显的并发症或复发。
改良自体移植物翼状胬肉切除术后可降低角膜散光,提高视力,与经典技术相当。术后 2 个月,角膜曲率变化稳定,此时可向患者提供眼镜矫正。