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葡萄糖-6-磷酸脱氢酶缺乏症与阴茎异常勃起:这两种病症之间存在关联吗?

G6PD Deficiency and Priapism: Is There a Link Between the Two Entities?

作者信息

Mufti Muhammad, Alvarez Laura, Marathe Omkar

机构信息

Department of Medicine, St. Mary Medical Center, Long Beach, CA, USA.

Department of Hematology/Oncology, St. Mary Medical Center, Long Beach, CA, USA.

出版信息

J Med Cases. 2019 Sep;10(9):271-273. doi: 10.14740/jmc3355. Epub 2019 Sep 26.

Abstract

Glucose 6 phosphate dehydrogenase (G6PD) is called the house keeping enzyme essential for all cells survival. G6PD deficiency is best studied for its role in hemolysis as this enzyme is the only source of nicotinamide adenine dinucleotide phosphate (NADPH) in red blood cells (RBCs) and is the cells defense against reactive oxygen species. We present one of the rare complications of G6PD deficiency in this case where all other causes of priapism were ruled out.

摘要

葡萄糖6磷酸脱氢酶(G6PD)被称为所有细胞生存所必需的管家酶。G6PD缺乏症因其在溶血中的作用而得到了充分研究,因为这种酶是红细胞(RBC)中烟酰胺腺嘌呤二核苷酸磷酸(NADPH)的唯一来源,也是细胞抵御活性氧的防御机制。在本病例中,我们呈现了G6PD缺乏症的一种罕见并发症,其中排除了所有其他导致阴茎异常勃起的原因。

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本文引用的文献

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Ischaemic Priapism and Glucose-6-Phosphate Dehydrogenase Deficiency: A Mechanism of Increased Oxidative Stress?
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