Department of Radiology, Clinical Imaging Physics Group, Duke University Medical Center, Durham, North Carolina, USA.
Clinical Imaging Physics Group, Carl E. Ravin Advanced Imaging Laboratories, Duke University Medical Center, Durham, North Carolina, USA.
J Appl Clin Med Phys. 2021 Oct;22(10):249-260. doi: 10.1002/acm2.13396. Epub 2021 Sep 2.
A novel routine dual-energy computed tomography (DECT) quality control (QC) program was developed to address the current deficiency of routine QC for this technology. The dual-energy quality control (DEQC) program features (1) a practical phantom with clinically relevant materials and concentrations, (2) a clinically relevant acquisition, reconstruction, and postprocessing protocol, and (3) a fully automated analysis software to extract quantitative data for database storage and trend analysis. The phantom, designed for easy set up for standalone or adjacent imaging next to the ACR phantom, was made in collaboration with an industry partner and informed by clinical needs to have four iodine inserts (0.5, 1, 2, and 5 mg/ml) and one calcium insert (100 mg/ml) equally spaced in a cylindrical water-equivalent background. The imaging protocol was based on a clinical DECT abdominal protocol capable of producing material specific concentration maps, virtual unenhanced images, and virtual monochromatic images. The QC automated analysis software uses open-source technologies which integrates well with our current automated CT QC database. The QC program was tested on a GE 750 HD scanner and two Siemens SOMATOM FLASH scanners over a 3-month period. The automated algorithm correctly identified the appropriate region of interest (ROI) locations and stores measured values in a database for monitoring and trend analysis. Slight variations in protocol settings were noted based on manufacturer. Overall, the project proved to provide a convenient and dependable clinical tool for routine oversight of DE CT imaging within the clinic.
开发了一种新的常规双能计算机断层扫描(DECT)质量控制(QC)程序,以解决该技术当前常规 QC 的不足。双能质量控制(DEQC)程序的特点是:(1)具有临床相关材料和浓度的实用体模;(2)具有临床相关的采集、重建和后处理协议;(3)具有全自动分析软件,可提取定量数据进行数据库存储和趋势分析。该体模与行业合作伙伴合作设计,易于与 ACR 体模独立或相邻成像设置,根据临床需求设计,具有四个碘插入物(0.5、1、2 和 5 mg/ml)和一个钙插入物(100 mg/ml),均匀分布在圆柱形水等效背景中。成像协议基于临床 DECT 腹部协议,能够生成物质特异性浓度图、虚拟非增强图像和虚拟单能图像。QC 自动分析软件使用开源技术,与我们当前的自动 CT QC 数据库集成良好。该 QC 程序在三个月的时间里在一台 GE 750 HD 扫描仪和两台西门子 SOMATOM FLASH 扫描仪上进行了测试。自动算法正确识别了适当的感兴趣区域(ROI)位置,并将测量值存储在数据库中,以便进行监测和趋势分析。根据制造商的不同,协议设置略有变化。总的来说,该项目证明了它为临床常规 DE CT 成像提供了一种方便可靠的临床工具。