一项关于5-氟尿嘧啶与滤过手术的前瞻性随机研究。
A prospective, randomized study of 5-fluorouracil and filtration surgery.
作者信息
Ruderman J M, Welch D B, Smith M F, Shoch D E
机构信息
Department of Ophthalmology, Northwestern University Medical School, Chicago, Illinois.
出版信息
Trans Am Ophthalmol Soc. 1987;85:238-53.
Abstract
Our study shows that use of a small dose of subconjunctival 5-FU provides significantly lower postoperative intraocular pressure than does no antimetabolite treatment. Morphology of the postoperative blebs suggests that increased filtration results in lower intraocular pressure in the 5-FU group. Corneal epithelial defects were as common with a low dose as with higher doses previously described.
摘要
我们的研究表明，与不使用抗代谢药物治疗相比，使用小剂量结膜下5-氟尿嘧啶（5-FU）可使术后眼压显著降低。术后滤过泡的形态表明，5-FU组中滤过增加导致眼压降低。角膜上皮缺损在低剂量时与先前描述的高剂量时一样常见。
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本文引用的文献
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Trabeculectomy in young patients.年轻患者的小梁切除术
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