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先天性子宫畸形产妇的真空辅助阴道分娩;危险因素和结局。

Vacuum-assisted vaginal deliveries among parturients with congenital uterine anomalies; risk factors and outcomes.

机构信息

Department of Obstetrics & Gynecology, Shaare Zedek Medical Center, Affiliated with the Hebrew University School of Medicine, Jerusalem, Israel.

Department of Obstetrics & Gynecology, Shaare Zedek Medical Center, Affiliated with the Hebrew University School of Medicine, Jerusalem, Israel.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2021 Oct;265:113-118. doi: 10.1016/j.ejogrb.2021.08.021. Epub 2021 Aug 26.

Abstract

OBJECTIVE

To evaluate the maternal and neonatal outcomes associated with vacuum-assisted vaginal delivery (VAVD) in a subset of parturients with congenital uterine anomalies.

STUDY DESIGN

A retrospective database study was conducted at a single tertiary center between 2005 and 2019. Parturients with known congenital uterine anomalies who had vaginal deliveries were enrolled, whereas parturients with failed VAVD, didelphic uterus, and delivery after intrauterine fetal death were excluded. Various maternal and neonatal outcomes were compared between parturients who achieved spontaneous vaginal delivery (SVD) and those who delivered via VAVD. The maternal composite outcome was calculated for each group and included one or more of the following: post-partum hemorrhage, hemoglobin drop ≥ 4 gr/dL, blood transfusions, retained placental products, and obstetric anal sphincter injuries. Univariate analysis was performed followed by multivariate logistic regression analysis controlling for potential confounders. Adjusted odds ratios (aORs) and 95% confidence intervals (CIs) were calculated.

RESULTS

After the application of the exclusion criteria, 332 parturients were found eligible. Of those, 289 (87%) had SVD and 43 (13%) had VAVD. VAVD was more common among primiparous parturients and epidural analgesia users. Parturients with VAVD had higher rates of third-degree perineal tear, postpartum hemorrhage, and blood transfusions. The maternal composite outcome was significantly more prevalent in the VAVD group (44.2% vs. 20.8%, p < 0.01). After controlling for potential confounders, the maternal composite outcome was found to be independently associated with VAVD (aOR 2.3, 95% CI 1.10-4.60). The neonatal results were overall comparable, except for scalp trauma and Erb's palsy/clavicular fracture, which were more prevalent in the VAVD group.

CONCLUSION

In a special population of parturients with congenital uterine anomalies, VAVD was found to be associated with significantly higher rates of adverse maternal outcomes and perinatal birth trauma. These findings should be presented to parturients during consultations about modes of delivery.

摘要

目的

评估先天性子宫畸形产妇中行真空辅助阴道分娩(VAVD)的母婴结局。

研究设计

这是一项在 2005 年至 2019 年期间在一家三级中心进行的回顾性数据库研究。纳入行阴道分娩且已知患有先天性子宫畸形的产妇,排除 VAVD 失败、双子宫和宫内胎儿死亡后分娩的产妇。比较自然分娩(SVD)和 VAVD 分娩产妇的各种母婴结局。计算每组的母体复合结局,包括以下一种或多种情况:产后出血、血红蛋白下降≥4g/dL、输血、胎盘残留和产科肛门括约肌损伤。进行单变量分析,然后进行多变量逻辑回归分析,控制潜在混杂因素。计算调整后的优势比(aOR)和 95%置信区间(CI)。

结果

应用排除标准后,共纳入 332 名产妇。其中 289 名(87%)为 SVD,43 名(13%)为 VAVD。初产妇和硬膜外镇痛使用者中 VAVD 更为常见。VAVD 组的三度会阴撕裂、产后出血和输血发生率更高。VAVD 组的母体复合结局明显更为常见(44.2%比 20.8%,p<0.01)。控制潜在混杂因素后,母体复合结局与 VAVD 独立相关(aOR 2.3,95%CI 1.10-4.60)。新生儿结果总体相似,仅头皮创伤和臂丛神经麻痹/锁骨骨折更为常见。

结论

在患有先天性子宫畸形的特殊产妇人群中,VAVD 与更高的不良母婴结局和围产儿出生创伤发生率相关。在讨论分娩方式时,应将这些发现告知产妇。

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