Department of Urology and Laboratory of Pelvic Floor Muscle Function, Shenzhen Children's Hospital, Futian District, Shenzhen, 518000, Guangdong, People's Republic of China.
World J Urol. 2022 Jan;40(1):155-160. doi: 10.1007/s00345-021-03829-9. Epub 2021 Sep 5.
Our study examined the benefit of an alternative interposition urethroplasty (IU) procedure for glandular hypospadias (GH) with severe penile curvature (SPC). The technique involved transecting and reconstructing the urethra to preserve the distal glandular and coronal urethra and correct the curvature. We compared procedural characteristics, outcomes, and surgical complications for the single-stage and staged IU techniques.
We retrospectively studied 44 patients with GH with SPC who underwent single-stage or staged IU between March 2005 and June 2020. Demographics, operative details, complications, and uroflometry findings were analyzed.
The median age at initial surgery was 37.5 months. Ten patients underwent single-stage IU repair, and 34 patients underwent staged IU repair. The median length of the interposition neourethra was 3.2 cm (2.2-4.3). The median follow-up duration was 58 months, and the overall complication rate was 13.6%. Complications were noted in 30% (3/10) and 8.8% (3/34) of patients in the single-stage and staged IU groups, respectively (p > 0.05). Fistula formation was noted in one and three patients in the single-stage and staged groups, respectively (8.8% vs. 10%, p > 0.05). Two cases of urethral stricture were documented in the single-stage group only. No chordee recurrence or urethral diverticula was noted in any of the patients.
IU is a reliable and durable technique for GH with SPC. It avoided penile shortening, preserved the distal urethra, and reduced the risk of chordee recurrence. The staged IU technique had more superior outcomes compared to the single-stage IU technique.
本研究探讨了替代间置尿道成形术(IU)治疗严重阴茎弯曲(SPC)伴性腺性尿道下裂(GH)的益处。该技术涉及切断和重建尿道,以保留远端腺体和冠状尿道并纠正弯曲。我们比较了单阶段和分期 IU 技术的手术特点、结果和手术并发症。
我们回顾性研究了 2005 年 3 月至 2020 年 6 月期间接受单阶段或分期 IU 治疗的 44 例 GH 伴 SPC 患者。分析了人口统计学、手术细节、并发症和尿流动力学发现。
初次手术时的中位年龄为 37.5 个月。10 例患者行单阶段 IU 修复,34 例患者行分期 IU 修复。间置新尿道的中位长度为 3.2cm(2.2-4.3)。中位随访时间为 58 个月,总并发症发生率为 13.6%。单阶段和分期 IU 组分别有 30%(3/10)和 8.8%(3/34)的患者发生并发症(p>0.05)。单阶段和分期组分别有 1 例和 3 例患者出现瘘管形成(8.8%比 10%,p>0.05)。单阶段组仅发生 2 例尿道狭窄。所有患者均未出现阴茎弯曲复发或尿道憩室。
IU 是治疗 SPC 伴 GH 的可靠且持久的技术。它避免了阴茎缩短,保留了远端尿道,降低了阴茎弯曲复发的风险。分期 IU 技术的效果优于单阶段 IU 技术。