社区获得性肺炎治疗后 30 天内复发相关因素的研究。
Study of factors related to recurrence within 30 days after pneumonia treatment for community-onset pneumonia.
机构信息
Department of Respiratory Medicine, Fukuoka University Chikushi Hospital, Chikushino, Fukuoka, Japan.
Department of Respiratory Medicine, Fukuoka University Chikushi Hospital, Chikushino, Fukuoka, Japan.
出版信息
J Infect Chemother. 2021 Dec;27(12):1683-1688. doi: 10.1016/j.jiac.2021.08.002. Epub 2021 Sep 2.
INTRODUCTION
It is not uncommon for patients hospitalized with pneumonia to experience an early relapse. Here, we investigated the factors related to pneumonia recurrence in Japan.
PURPOSE
We aimed to elucidate the factors related to early recurrence after completion of pneumonia treatment.
METHODS
We examined 696 patients with community-acquired pneumonia (CAP) and nursing and healthcare-associated pneumonia (NHCAP) who were admitted to our hospital between October 2010 and February 2018, excluding those who died during hospitalization. Logistic regression analysis was used to assess the endpoint of recurrence within 30 days after the end of antibiotic treatment.
RESULTS
NHCAP, chronic lung disease and duration of antibiotic treatment were significant risk factors for recurrence of pneumonia within 30 days after antibiotic discontinuation. Aspiration pneumonia was not be a significant factor in the early recurrence of pneumonia.
CONCLUSIONS
Long-term use of antimicrobials may be a risk factor in early recurrence of pneumonia.
简介
肺炎住院患者早期复发并不少见。在此，我们调查了与日本肺炎复发相关的因素。
目的
阐明肺炎治疗完成后早期复发的相关因素。
方法
我们检查了 2010 年 10 月至 2018 年 2 月期间因社区获得性肺炎（CAP）和护理相关性肺炎（NHCAP）住院的 696 例患者，不包括住院期间死亡的患者。使用逻辑回归分析评估抗生素治疗结束后 30 天内复发的终点。
结果
NHCAP、慢性肺病和抗生素治疗时间是抗生素停药后 30 天内肺炎复发的显著危险因素。吸入性肺炎不是肺炎早期复发的显著因素。
结论
长期使用抗菌药物可能是肺炎早期复发的一个危险因素。
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