Song Ying-Hao, Xu Ruo-Xin, Zhang Yong, Xing Meng-Xuan, Xu Li-Dong, Li Kun-Kun, Xiao Xing-Guo, Li Lu, Xiao Yan-Jing, Qu Yu-Lei, Ma Ying-Jie, Jia Bao-Hui, Wu Hui-Li
Department of Gastroenterology, People's Hospital of Henan University of Chinese Medicine, Henan University of Chinese Medicine, Zhengzhou, 450000 Henan Province, China.
Department of Gastroenterology, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou University, Zhengzhou, 450000 Henan Province, China.
Gastroenterol Res Pract. 2021 Aug 27;2021:5533657. doi: 10.1155/2021/5533657. eCollection 2021.
Magnifying chromoendoscopy (ME-CE) through the observation of pit patterns is a productive way to distinguish between neoplastic and nonneoplastic polyps. Magnifying optical enhancement technology (ME-OE) is an emerging virtual chromoendoscopy imaging technology and appeared to be a promising approach. However, this information is currently not available. This study is aimed at comparing the differential diagnostic value of ME-CE and OE for neoplastic and nonneoplastic polyps. . Consecutive patients undergoing colonoscopy were randomized (1 : 1) into examination by ME-OE or ME-CE. Histopathological findings were utilized as the reference standard. Accuracy, sensitivity, specificity, and positive and negative predictive values of two endoscopy methods were compared using ME-OE (were classified according to the JNET classification) and ME-CE (were classified according to the Kudo pit pattern classification), respectively, and the time to predict the histological polyp type was compared. And the agreements between the pathological and clinical diagnosis by ME-OE or ME-CE were analyzed.
A total of 365 polyps were found in the 220 patients included (ME-OE: 185; ME-CE: 180.202 had nonneoplastic polyps, 163 had neoplastic polyps). The diagnostic accuracy of ME-OE was higher than that of ME-CE (93% vs. 92%, > 0.05). The average diagnosis time was lower in ME-OE than ME-CE (83 ± 26.4 s vs. 194 ± 17.7 s, < 0.001). The agreements between the pathological and clinical diagnosis were at least substantial in both groups.
ME-OE was superlative to ME-CE in predicting the histology of polyps. OE devoted classification would possibly similarly enhance the endoscopist performance. The trial is registered with ChiCT2000032075.
通过观察凹坑形态的放大染色内镜检查（ME-CE）是区分肿瘤性和非肿瘤性息肉的有效方法。放大光学增强技术（ME-OE）是一种新兴的虚拟染色内镜成像技术，似乎是一种有前景的方法。然而，目前尚无相关信息。本研究旨在比较ME-CE和OE对肿瘤性和非肿瘤性息肉的鉴别诊断价值。连续接受结肠镜检查的患者被随机（1∶1）分为接受ME-OE或ME-CE检查。组织病理学结果用作参考标准。分别使用ME-OE（根据JNET分类）和ME-CE（根据工藤凹坑形态分类）比较两种内镜检查方法的准确性、敏感性、特异性以及阳性和阴性预测值，并比较预测息肉组织学类型的时间。分析ME-OE或ME-CE的病理诊断与临床诊断之间的一致性。
纳入的220例患者共发现365个息肉（ME-OE：185个；ME-CE：180个。202个为非肿瘤性息肉，163个为肿瘤性息肉）。ME-OE的诊断准确性高于ME-CE（93%对92%，P>0.05）。ME-OE的平均诊断时间低于ME-CE（83±26.4秒对194±17.7秒，P<0.001）。两组病理诊断与临床诊断之间的一致性至少为实质性。
在预测息肉组织学方面，ME-OE优于ME-CE。OE专用分类可能同样会提高内镜医师的表现。该试验已在ChiCT2000032075注册。
