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一例原发性全膝关节置换术中伴金属沉着症的骨质溶解有趣病例。

An Interesting Case of Osteolysis With Accompanying Metallosis in a Primary Total Knee Arthroplasty.

作者信息

Lamba Collin, Denning Krista, Ouellette Eric, Kurtz Steven, Bullock Matthew

机构信息

Department of Orthopaedics, Marshall University, Joan C. Edwards School of Medicine, Huntington, WV.

Department of Pathology, Marshall University, Joan C. Edwards School of Medicine, Huntington, WV.

出版信息

Arthroplast Today. 2021 Aug 26;11:81-87. doi: 10.1016/j.artd.2021.07.002. eCollection 2021 Oct.

Abstract

Arthroplasty implants are comprised of metal alloys designed to function within the human body. Implant-related issues and associated soft-tissue reactions have been well documented for modular revision hip and knee constructs. This case highlights findings of metallosis in the context of polyethylene wear in a failed primary total knee arthroplasty. Fretting of a polyethylene reinforcement pin within the tibial baseplate as a direct result of knee joint instability appears to be the root cause of observed periprosthetic metallosis. Enhanced design principles and improved polyethylene locking mechanisms may be useful to potentially mitigate fretting-related issues in future knee replacement designs. The authors recommend surveillance in patients with this construct especially when prosthetic instability is present.

摘要

关节置换植入物由设计用于在人体中发挥功能的金属合金组成。对于模块化翻修髋关节和膝关节结构,与植入物相关的问题及相关软组织反应已有充分记录。本病例突出了在初次全膝关节置换失败且伴有聚乙烯磨损的情况下金属沉着病的发现。膝关节不稳定直接导致胫骨基板内的聚乙烯加强销微动,这似乎是观察到的假体周围金属沉着病的根本原因。改进设计原则和完善聚乙烯锁定机制可能有助于在未来膝关节置换设计中潜在地减轻与微动相关的问题。作者建议对采用这种结构的患者进行监测,尤其是在存在假体不稳定的情况下。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c00e/8397922/f06188c654f2/gr1.jpg

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