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内镜与显微镜耳科学手术后的术后疼痛:系统评价和荟萃分析。

Postoperative Pain After Endoscopic vs Microscopic Otologic Surgery: A Systematic Review and Meta-analysis.

机构信息

California Northstate University, College of Medicine, Elk Grove, California, USA.

Department of Otolaryngology-Head and Neck Surgery, Kaiser Permanente Oakland Medical Center, Oakland, California, USA.

出版信息

Otolaryngol Head Neck Surg. 2022 Jul;167(1):25-34. doi: 10.1177/01945998211041946. Epub 2021 Sep 7.

Abstract

OBJECTIVE

Equivalent outcomes, such as procedural safety and audiometry, have been reported between endoscopic ear surgery (EES) and microscopic ear surgery (MES). This study aims to determine if EES leads to decreased postoperative pain when compared with MES.

DATA SOURCES

PubMed, OVID MEDLINE, Scopus, Web of Science, and Cochrane Central from 2000 to 2020.

REVIEW METHODS

A systematic review in accordance with the PRISMA guidelines and standardized bias assessment was performed. Studies containing original data on postoperative pain following EES and MES were included.

RESULTS

Fourteen studies fulfilled eligibility: 7 retrospective studies, 6 randomized controlled trials, and 1 case series. Studies included surgery for cholesteatoma (n = 3), tympanoplasty/myringoplasty (n = 6), and stapedotomy (n = 5), pooling data from 974 patients. Postoperative pain was quantitatively described through a variety of numeric pain scores. Meta-analysis was performed on 11 studies. Among the 7 studies utilizing the numeric rating scale or visual analog scale, postoperative pain in the EES cohort was significantly lower than that of the MES cohort (standardized mean difference = -1.45 [95% CI, -2.05 to -0.85], < .001). Similarly, pain scores were lower in the EES cohort among the 4 studies utilizing the Three Grades Pain Scale (odds ratio = 0.2 [95% CI, 0.09-0.45], < .001). Additional qualitative strengths identified in EES included significant improvements in visualization, operative time, postoperative complications, and decreased need for canalplasty. Quality assessment indicated low to moderate risk of bias for all studies.

CONCLUSION

Meta-analysis confirms that EES results in significantly less postoperative pain when compared with MES. This surgical approach should be considered in the armamentarium of otologic surgeons, allowing for improved outcomes.

摘要

目的

内镜耳部手术(EES)与显微镜耳部手术(MES)的手术安全性和听力测试结果相当。本研究旨在确定 EES 是否比 MES 术后疼痛减轻。

数据来源

2000 年至 2020 年期间,PubMed、OVID MEDLINE、Scopus、Web of Science 和 Cochrane Central 数据库。

研究方法

根据 PRISMA 指南进行系统评价,并进行标准化偏倚评估。纳入包含 EES 和 MES 术后疼痛的原始数据的研究。

结果

14 项研究符合纳入标准:7 项回顾性研究、6 项随机对照试验和 1 项病例系列研究。研究包括胆脂瘤(n = 3)、鼓室成形术/鼓膜成形术(n = 6)和镫骨切除术(n = 5)手术,共纳入 974 例患者。术后疼痛通过各种数字疼痛评分进行定量描述。对 11 项研究进行了荟萃分析。在使用数字评分量表或视觉模拟量表的 7 项研究中,EES 组的术后疼痛明显低于 MES 组(标准化均数差=-1.45[95%CI,-2.05 至-0.85],<.001)。同样,在使用三级疼痛量表的 4 项研究中,EES 组的疼痛评分也较低(比值比=0.2[95%CI,0.09-0.45],<.001)。EES 的其他定性优势包括可视化、手术时间、术后并发症和需要 canalplasty 的明显改善。所有研究的质量评估均表明存在低到中度偏倚风险。

结论

荟萃分析证实 EES 与 MES 相比,术后疼痛明显减轻。这种手术方法应被纳入耳科医生的治疗方案中,以获得更好的结果。

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