先天性心脏病新生儿延迟关胸术后手术部位感染：回顾性病例对照研究。
Surgical site infection after delayed sternal closure in neonates with congenital heart disease: retrospective case-control study.
机构信息
Department of Cardiothoracic Surgery, Children's Hospital of Nanjing Medical University, No.72 Guangzhou Road, Nanjing, Jiangsu Province, People's Republic of China, 210008.
Department of General Surgery and Ear-Nose-Throat, Children's Hospital of Nanjing Medical University, Nanjing, China.
出版信息
Ital J Pediatr. 2021 Sep 8;47(1):182. doi: 10.1186/s13052-021-01138-w.
OBJECTIVES
To determine the prevalence of surgical site infections (SSIs) in neonatal congenital heart disease patients undergoing delayed sternal closure (DSC) and evaluate risk factors for SSI.
METHODS
Hospital records of 483 consecutive neonates who underwent surgical intervention between January 2013 and December 2017 were reviewed, and perioperative variables were recorded.
RESULTS
We found that the prevalence of SSI was 87.5% when the body weight was less than 1500 g. When the operative age was between seven and 14 days, the probability of no SSI is about 93.9%. When the duration of the aortic cross-clamp was more than 60 min, the prevalence of SSI was 91.2%. The prevalence without SSI was 96.6% when the duration of DSC was less than 24 h. However, when the duration of DSC was more than 120 h, the prevalence of SSI was 88.9% (p = 0.000).
CONCLUSIONS
With the prolongation of aortic clamping duration, the probability of occurrence of SSI increased in neonatal CHD with DSC. The age at operation and body weight are closely related to the occurrence of SSI in neonatal CHD patients with DSC.
目的
确定行延迟关胸术（DSC）的新生儿先天性心脏病患者的手术部位感染（SSI）发生率，并评估 SSI 的危险因素。
方法
回顾了 2013 年 1 月至 2017 年 12 月期间连续 483 例接受手术干预的新生儿的医院记录，并记录了围手术期变量。
结果
我们发现体重小于 1500g 时 SSI 的发生率为 87.5%。当手术年龄在 7 至 14 天时，无 SSI 的概率约为 93.9%。当主动脉阻断时间超过 60 分钟时，SSI 的发生率为 91.2%。当 DSC 时间小于 24 小时时，无 SSI 的发生率为 96.6%。然而，当 DSC 时间超过 120 小时时，SSI 的发生率为 88.9%（p=0.000）。
结论
随着主动脉夹闭时间的延长，行 DSC 的新生儿 CHD 患者发生 SSI 的概率增加。手术年龄和体重与行 DSC 的新生儿 CHD 患者 SSI 的发生密切相关。
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