Sviridov A F, Romanovich A Iu, Chizhov O S
Bioorg Khim. 1987 Dec;13(12):1665-71.
Strategy of synthesis of polyene macrolide antibiotic amphotericin B using carbohydrates as starting material is discussed. The C1-C6 and C7-C12 fragments of amphotericin B are synthesized.
讨论了以碳水化合物为起始原料合成多烯大环内酯类抗生素两性霉素B的策略。合成了两性霉素B的C1-C6和C7-C12片段。