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小儿嗜酸性粒细胞性食管炎的内镜检查

Endoscopy in Pediatric Eosinophilic Esophagitis.

作者信息

Nguyen Nathalie, Kramer Robert E, Menard-Katcher Calies

机构信息

Department of Pediatrics, Digestive Health Institute, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, CO, United States.

出版信息

Front Pediatr. 2021 Aug 24;9:713027. doi: 10.3389/fped.2021.713027. eCollection 2021.

Abstract

Endoscopy and mucosal biopsies are essential to the diagnosis of EoE. Together they either confirm or exclude mucosal eosinophilia and provide a visual inspection of the esophagus that may be consistent with EoE or suggest other underlying etiologies. Endoscopy also plays an important therapeutic role in the management of EoE including the assessment of treatment response and treatment of associated complications including esophageal stricture and food impaction. Assessment of treatment response largely depends on endoscopy and mucosal biopsies although less invasive strategies may eventually provide alternative means to assess mucosal inflammation. Herein we will review current use of endoscopy in EoE, including recently developed technologies and their role in the management of EoE.

摘要

内镜检查和黏膜活检对于嗜酸性食管炎(EoE)的诊断至关重要。它们共同作用,要么证实要么排除黏膜嗜酸性粒细胞增多,并对食管进行可视检查,这可能与EoE相符或提示其他潜在病因。内镜检查在EoE的管理中也发挥着重要的治疗作用,包括评估治疗反应以及治疗相关并发症,如食管狭窄和食物嵌塞。治疗反应的评估很大程度上依赖于内镜检查和黏膜活检,尽管侵入性较小的策略最终可能提供评估黏膜炎症的替代方法。在此,我们将回顾目前内镜检查在EoE中的应用,包括最近开发的技术及其在EoE管理中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e50a/8421673/e947ea6cf908/fped-09-713027-g0001.jpg

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