Department of Neurosurgery, Spine Center, Kyung Hee University Hospital at Gangdong, Seoul, Korea.
Department of Orthopedic Surgery, Chuncheon Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea.
PLoS One. 2021 Sep 10;16(9):e0257316. doi: 10.1371/journal.pone.0257316. eCollection 2021.
Adult spinal deformity (ASD) is usually rigid and requires a combined anterior-posterior approach for deformity correction. Anterior lumbar interbody fusion (ALIF) allows direct access to the disc space and placement of a large interbody graft. A larger interbody graft facilitates correction of ASD. However, an anterior approach carries significant risks. Lateral lumbar interbody fusion (LLIF) through a minimally invasive approach has recently been used for ASD. The present study was performed to evaluate the effectiveness of oblique lumbar interbody fusion (OLIF) in the treatment of ASD. We performed a retrospective study utilizing the data of 74 patients with ASD. The inclusion criteria were lumbar coronal Cobb angle > 20°, pelvic incidence (PI)-lumbar lordosis (LL) mismatch > 10°, and minimum follow-up of 2 years. Patients were divided into two groups: ALIF combined with posterior spinal fixation (ALIF+PSF) (n = 38) and OLIF combined with posterior spinal fixation (OLIF+PSF) (n = 36). The perioperative spinal deformity radiographic parameters, complications, and health-related quality of life (HRQoL) outcomes were assessed and compared between the two groups. The preoperative sagittal vertical axis (SVA), LL, PI-LL mismatch, and lumbar Cobb angles were similar between the two groups. Patients in the OLIF+PSF group had a slightly higher mean number of interbody fusion levels than those in the ALIF+PSF group. At the final follow-up, all radiographic parameters and HRQoL scores were similar between the two groups. However, the rates of perioperative complications were higher in the ALIF+PSF than OLIF+PSF group. The ALIF+PSF and OLIF+PSF groups showed similar radiographic and HRQoL outcomes. These observations suggest that OLIF is a safe and reliable surgical treatment option for ASD.
成人脊柱畸形(ASD)通常较为僵硬,需要前后联合入路进行矫正。前路腰椎间融合术(ALIF)可直接进入椎间盘间隙,并放置较大的椎间植骨。较大的椎间植骨有助于 ASD 的矫正。然而,前路入路存在较大的风险。通过微创入路进行的侧方腰椎间融合术(LLIF)最近已用于 ASD 的治疗。本研究旨在评估斜侧腰椎间融合术(OLIF)在 ASD 治疗中的有效性。我们进行了一项回顾性研究,纳入了 74 例 ASD 患者的数据。纳入标准为腰椎冠状 Cobb 角>20°、骨盆入射角(PI)-腰椎前凸角(LL)不匹配>10°,且随访时间至少 2 年。患者分为两组:前路腰椎间融合术联合后路脊柱固定术(ALIF+PSF)(n = 38)和 OLIF 联合后路脊柱固定术(OLIF+PSF)(n = 36)。评估并比较两组患者的围手术期脊柱畸形影像学参数、并发症和健康相关生活质量(HRQoL)结局。两组患者的术前矢状垂直轴(SVA)、LL、PI-LL 不匹配和腰椎 Cobb 角相似。OLIF+PSF 组患者的平均椎间融合节段数略高于 ALIF+PSF 组。末次随访时,两组患者的所有影像学参数和 HRQoL 评分均相似。然而,ALIF+PSF 组的围手术期并发症发生率高于 OLIF+PSF 组。ALIF+PSF 组和 OLIF+PSF 组的影像学和 HRQoL 结果相似。这些观察结果表明,OLIF 是 ASD 安全可靠的手术治疗选择。