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血管内超声对钝性胸主动脉损伤的胸主动脉腔内修复术后临床结局的影响。

Effect of intravascular ultrasound on clinical outcomes after thoracic endovascular aortic repair for blunt thoracic aortic injury.

机构信息

Division of Vascular Surgery and Endovascular Therapy, Department of Surgery, Case Western Reserve University School of Medicine, University Hospitals Cleveland Medical Center, Cleveland, Ohio.

Research in Surgical Outcomes and Effectiveness, Department of Surgery, University Hospitals Cleveland Medical Center, Cleveland, Ohio.

出版信息

J Vasc Surg. 2022 Feb;75(2):448-454.e2. doi: 10.1016/j.jvs.2021.08.061. Epub 2021 Sep 8.

Abstract

OBJECTIVE

Thoracic endovascular aortic repair (TEVAR) for blunt traumatic aortic injuries (BTAIs) can be complicated by inaccurate aortic measurements at the initial computed tomography angiography secondary to hypovolemic shock. The use of intravascular ultrasound (IVUS) has been proposed for more accurate aortic sizing, with prior data demonstrating larger aortic sizes measured by IVUS, potentially altering the vast majority of chosen endograft sizes. At present, and to the best of our knowledge, no studies have examined whether IVUS affects the clinical outcomes. The purpose of the present study was to examine the effect of IVUS on the clinical outcomes after TEVAR for BTAIs.

METHODS

A retrospective cohort study was performed of patients who had undergone TEVAR for BTAIs in the VQI registry. The cohorts were defined by the use of IVUS. The primary outcomes were mortality and reintervention at 1 year.

RESULTS

A total of 919 patients who had undergone TEVAR for BTAIs were included in the present analysis. The IVUS patients had presented with higher injury severity scores (36.2 vs 42; P = .0004) largely because of more extremity and external trauma. IVUS was more often used for patients with grade III injuries (49.1% vs 56.9%; P = .02) and less often for patients with rupture (21.1% vs 12.4%; P = .001). A trend toward a delay in TEVAR was seen for the patients for whom IVUS was used (1.8 vs 3.5 days; P = .38), with additional trends toward reduced intraoperative resuscitation and blood loss. The hemodynamic status of the patients and differences in aortic or endograft sizes could not be assessed with the available data. IVUS use was not associated with any differences in survival or reintervention rates in-hospital or at 1 year (Kaplan-Meier survival estimates: 0.91 no IVUS vs 0.92 IVUS; P = .46). Fifteen aortic-related reinterventions occurred across the entire patient cohort for all-available follow-up with comparable rates of type I endoleaks (1 no IVUS vs 2 IVUS), with no recorded cases of sizing-related complications such as device rupture, migration, or dissection.

CONCLUSIONS

IVUS usage during TEVAR for BTAIs was associated with clinical scenarios in which patients were more stable and interventions to address BTAIs can be delayed. Despite this, the overall clinical outcomes were similar between cases in which IVUS was used and for which it was not.

摘要

目的

在因低血容量性休克导致初始计算机断层血管造影术(CTA)测量不准确的情况下,胸主动脉腔内修复术(TEVAR)治疗钝性创伤性主动脉损伤(BTAI)可能会变得复杂。血管内超声(IVUS)的使用可进行更准确的主动脉测量,先前的数据显示 IVUS 测量的主动脉尺寸更大,这可能会改变绝大多数选择的移植物尺寸。目前,据我们所知,尚无研究探讨 IVUS 是否会影响临床结局。本研究的目的是研究 IVUS 在 TEVAR 治疗 BTAI 后的临床结局中的影响。

方法

对 VQI 注册中心接受 TEVAR 治疗 BTAI 的患者进行回顾性队列研究。通过 IVUS 使用对队列进行定义。主要结局为 1 年时的死亡率和再介入。

结果

本分析共纳入 919 例接受 TEVAR 治疗 BTAI 的患者。IVUS 患者的损伤严重程度评分更高(36.2 比 42;P=0.0004),主要是因为四肢和外部创伤更多。IVUS 更常用于 III 级损伤患者(49.1%比 56.9%;P=0.02),而用于破裂患者的情况较少(21.1%比 12.4%;P=0.001)。对于使用 IVUS 的患者,TEVAR 的延迟趋势可见(1.8 比 3.5 天;P=0.38),术中复苏和出血量减少的趋势也存在。无法用现有数据评估患者的血流动力学状态以及主动脉或移植物的大小差异。IVUS 的使用与住院期间或 1 年时的生存率或再介入率均无差异(Kaplan-Meier 生存估计值:无 IVUS 为 0.91,IVUS 为 0.92;P=0.46)。在整个患者队列的所有可获得的随访中,有 15 例发生主动脉相关的再介入,I 型内漏的发生率相似(无 IVUS 为 1 例,IVUS 为 2 例),没有记录到与尺寸相关的并发症,如器械破裂、迁移或夹层。

结论

在 BTAI 的 TEVAR 中使用 IVUS 与患者更稳定的临床情况相关,并且可以延迟处理 BTAI 的干预措施。尽管如此,在使用 IVUS 和未使用 IVUS 的病例中,总体临床结局相似。

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