Department of Otolaryngology-Head and Neck Surgery, University of California Davis Medical Center, Sacramento, California, USA.
Curr Opin Otolaryngol Head Neck Surg. 2021 Dec 1;29(6):473-478. doi: 10.1097/MOO.0000000000000757.
To review the recent literature on indications for and functional outcomes following laryngectomy for severe laryngeal dysfunction.
The use of functional laryngectomy as a definitive treatment for severe laryngeal dysfunction is increasing as more patients with head and neck cancer are treated with definitive chemoradiotherapy. Data are emerging on the efficacy of this technique as measured by aspiration, recurrent pneumonias, enteral tube feeding dependence, and surgical complication rates. Though most patients have marked improvement in aspiration and oral intake, difficulties in swallowing and voicing functions may persist.
Functional laryngectomy is an effective treatment for end-stage laryngeal dysfunction. There is a clear benefit with regard to prevention of aspiration and alleviation of nothing by mouth status. However, qualitative speech and swallowing outcomes are less well studied, though available data suggest that many patients still suffer some degree of continued chronic impairment. More research is needed on these outcomes in order to appropriately counsel patients regarding long-term functional outcomes.
回顾关于因严重喉部功能障碍而行喉切除术的适应证和功能结果的近期文献。
随着越来越多的头颈部癌症患者接受根治性放化疗,将功能性喉切除术作为严重喉部功能障碍的确定性治疗方法的应用正在增加。关于该技术的疗效数据正在不断涌现,其测量指标包括误吸、反复肺炎、肠内管饲依赖和手术并发症发生率。尽管大多数患者的误吸和经口进食情况明显改善,但吞咽和发声功能仍可能存在困难。
功能性喉切除术是治疗终末期喉部功能障碍的有效方法。在预防误吸和缓解不能经口进食方面有明显的益处。然而,关于定性言语和吞咽结果的研究较少,尽管现有数据表明,许多患者仍存在一定程度的持续慢性损害。需要对这些结果进行更多的研究,以便为患者提供有关长期功能结果的适当咨询。