1,25 - 二羟维生素D3和高钙对甲状旁腺激素原基因转录的影响是直接的。 - Suppr | 超能文献

The effects of 1,25-dihydroxyvitamin D3 and high calcium on transcription of the pre-proparathyroid hormone gene are direct.

作者信息

Russell J, Sherwood L M

机构信息

Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461.

出版信息

Trans Assoc Am Physicians. 1987;100:256-62.

Abstract

摘要

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The effects of 1,25-dihydroxyvitamin D3 and high calcium on transcription of the pre-proparathyroid hormone gene are direct.1,25 - 二羟维生素D3和高钙对甲状旁腺激素原基因转录的影响是直接的。

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1,25-Dihydroxyvitamin D3 has opposite effects on the expression of parathyroid secretory protein and parathyroid hormone genes.1,25-二羟基维生素D3对甲状旁腺分泌蛋白和甲状旁腺激素基因的表达具有相反的作用。

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引用本文的文献

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Hypocalcemia increases and hypercalcemia decreases the steady-state level of parathyroid hormone messenger RNA in the rat.低钙血症会使大鼠甲状旁腺激素信使核糖核酸的稳态水平升高，而高钙血症则会使其降低。

J Clin Invest. 1989 Mar;83(3):1053-6. doi: 10.1172/JCI113946.