嵌合 RNA 对人类细胞产生表型可塑性的进化影响。
Evolutionary impact of chimeric RNAs on generating phenotypic plasticity in human cells.
机构信息
Cancer Genomics and BioComputing of Complex Diseases Lab, Azrieli Faculty of Medicine, Bar-Ilan University, Safed 1311502, Israel.
出版信息
Trends Genet. 2022 Jan;38(1):4-7. doi: 10.1016/j.tig.2021.08.015. Epub 2021 Sep 24.
PMID:34579972
Abstract
Chimeric RNAs are generated by the fusion of the exons or introns of two genes. The generation of chimeric RNAs is important for the functional expansion of cells. Here, we describe the functional implications of chimeric RNAs for generating phenotypic plasticity from an evolutionary perspective.
摘要
嵌合 RNA 是由两个基因的外显子或内含子融合而成的。嵌合 RNA 的产生对于细胞的功能扩展很重要。在这里，我们从进化的角度描述了嵌合 RNA 对产生表型可塑性的功能意义。
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