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经直肠超声判断宫颈癌 GTV 的临床价值。

Clinical values of transrectal ultrasound in judging GTV of cervical cancer.

机构信息

Department of Ultrasound, China-Japan Union Hospital, Jilin University, Changchun, China.

Department of Radiotherapy, China-Japan Union Hospital, Jilin University, Changchun, China.

出版信息

Brachytherapy. 2021 Nov-Dec;20(6):1172-1179. doi: 10.1016/j.brachy.2021.07.007. Epub 2021 Sep 26.

Abstract

PURPOSE

To investigate the clinical value of transrectal ultrasound in judging the Gross Target Volume (GTV) of cervical cancer (CC).

METHODS

A total of 196 CC patients admitted to the Department of Radiotherapy, China-Japan Union Hospital, Jilin University, from January 2016 to June 2019 were selected as the study subjects. The GTVs before and after applicator insertion were determined by transrectal ultrasound and compared with those judged by MRI.

RESULTS

All 196 patients were successfully undergoing applicator insertion according to the pretreatment plan. The GTV doses reached the clinical requirements during treatment. There was no significant difference between the GTVs judged by MRI and ultrasound before insertion in terms of upper/lower diameter (MRI Before 1 vs. Ultrasound Before 1) (MB1 vs. UB1), left/right diameter (MB2 vs. UB2), or ventral/dorsal diameter (MB3 vs. UB3), and the intragroup correlation coefficients (ICC) were 0.59, 0.77, and 0.66, respectively; moreover, there was no significant difference between the GTVs judged by MRI and ultrasound after insertion in terms of MRI After one vs. Ultrasound After one (MA1 vs. UA1), MA2 vs. UA2, and MA3 vs. UA3, and the ICC values were 0.62, 0.79, and 0.76, respectively.

CONCLUSIONS

Transrectal ultrasound can satisfactorily determine the GTV of CC and has certain value in brachytherapy for CC.

摘要

目的

探讨经直肠超声在判断宫颈癌(CC)大体肿瘤靶区(GTV)中的临床价值。

方法

选取 2016 年 1 月至 2019 年 6 月期间在吉林大学中日联谊医院放疗科就诊的 196 例 CC 患者作为研究对象,通过经直肠超声判断宫旁插植前后 GTV,并与 MRI 进行对比。

结果

所有患者均按治疗前计划顺利完成施源器的插入。治疗过程中,GTV 剂量达到临床要求。MRI 前判断与超声前判断的上下径(MB1 与 UB1)、左右径(MB2 与 UB2)、前后径(MB3 与 UB3)GTV 差异均无统计学意义(均 P>0.05),组内相关系数分别为 0.59、0.77、0.66;MRI 后判断与超声后判断的 GTV 差异也均无统计学意义(均 P>0.05),组内相关系数分别为 0.62、0.79、0.76。

结论

经直肠超声能较好地判断 CC 的 GTV,在 CC 近距离治疗中具有一定的应用价值。

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