Department of Anesthesia and Perioperative Medicine, Medical University of South Carolina, Charleston, SC.
Department of Anesthesia and Perioperative Medicine, Medical University of South Carolina, Charleston, SC.
J Cardiothorac Vasc Anesth. 2022 Feb;36(2):542-545. doi: 10.1053/j.jvca.2021.09.016. Epub 2021 Sep 17.
Pregnancy entails significant changes in maternal physiology that are not well-tolerated in patients with pulmonary arterial hypertension. The profound changes in plasma volume, cardiac output, and systemic vascular resistance can lead to increased strain placed on the right ventricle, leading to right-heart failure and cardiovascular collapse. Given the complex and sometimes opposing physiologic changes, managing these patients can be challenging. As such, these patients have a significantly increased reported maternal mortality rate. This report describes a parturient with newly diagnosed severe pulmonary arterial hypertension and her anesthetic management.
妊娠会导致母体生理学发生重大变化,而这些变化在肺动脉高压患者中不能很好地耐受。血浆容量、心输出量和全身血管阻力的巨大变化可导致右心室负荷增加,导致右心衰竭和心血管崩溃。鉴于复杂且有时相互矛盾的生理变化,管理这些患者具有挑战性。因此,这些患者的报告母体死亡率明显增加。本报告描述了一位新诊断为严重肺动脉高压的产妇及其麻醉管理。