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联合延长术治疗获得性肢体长度差异:羟基磷灰石涂层髓内钉有优势吗?

Combined lengthening for acquired leg length discrepancy: Are there advantages of hydroxyapatite-coated intramedullary nails?

机构信息

Ilizarov National Medical Center for Traumatology and Orthopaedics, Kurgan, Russian Federation.

Department of Orthopaedics, Children's Orthopaedics and Traumatology Medical Center of Postgraduate Education, Otwock, Poland.

出版信息

Orthop Traumatol Surg Res. 2023 May;109(3):103101. doi: 10.1016/j.otsr.2021.103101. Epub 2021 Oct 7.

Abstract

INTRODUCTION

The aim of this multicenter prospective study was to analyze the outcomes of bone lengthening by external fixator associated with flexible intramedullary nailing (FIN) in acquired limb length discrepancy (LLD).

HYPOTHESIS

Hydroxyapatite (HA)-coated FIN enables reduced External Fixation Index in limb lengthening for acquired leg length discrepancies in comparison to non-HA-coated FIN.

MATERIAL AND METHODS

This study included 54 patients (mean age, 17.9 years) operated on for femoral or tibial lengthening by combined technique (External fixator with FIN) for acquired length discrepancy. Titanium non-HA-coated FIN (29 cases) or HA-coated FIN (25 cases) were used. The factors that might influence external fixation index, complication occurrence and outcome were analyzed: age, amount of lengthening, nail diameter, HA-coating vs. non-HA-coated nails.

RESULTS

The mean External Fixation Indexes (EFI) of groups compared for non-HA-coated nails vs. HA-coated nails were not significantly different: 26.5 d/cm and 27.2 d/cm in femoral lengthening and 34.9 d/cm and 31.7 d/cm in tibial lengthening. Positive correlation between the "nail diameter/inner distance between cortices at osteotomy site" ratio and EFI in tibial lengthening was revealed (p=0.034). The nail types and the "nail diameter/medullary canal diameter" ratio interact and have significant simultaneous effect on EFI in femoral lengthening (p=0.021).

DISCUSSION

The results of this study revealed no differences with regards to EFI using HA-coated or non-HA-coated titanium FIN in lengthening for acquired leg-length discrepancies. Combined technique allowed reduced EFI and avoided major complications. Both non-HA-nail and HA-coated nail lengthening provided good and excellent outcomes.

LEVEL OF EVIDENCE

III; (controlled trial without randomization) prospective comparative study.

摘要

简介

本多中心前瞻性研究旨在分析外固定架联合弹性髓内钉(FIN)治疗获得性肢体长度差异(LLD)的骨延长效果。

假说

与非 HA 涂层 FIN 相比,HA 涂层 FIN 可降低肢体延长的外固定指数(EFI),用于治疗获得性肢体长度差异。

材料和方法

本研究纳入了 54 例(平均年龄 17.9 岁)接受股骨或胫骨延长术的患者,采用联合技术(外固定架联合 FIN)治疗获得性长度差异。使用钛非 HA 涂层 FIN(29 例)或 HA 涂层 FIN(25 例)。分析可能影响外固定指数、并发症发生和结果的因素:年龄、延长量、钉直径、HA 涂层与非 HA 涂层钉。

结果

非 HA 涂层钉与 HA 涂层钉相比,股骨延长组和胫骨延长组的平均 EFI 无显著差异:分别为 26.5 d/cm 和 27.2 d/cm,34.9 d/cm 和 31.7 d/cm。胫骨延长中发现“钉直径/骨切开部位皮质内距离”比值与 EFI 呈正相关(p=0.034)。钉类型和“钉直径/髓腔直径”比值相互作用,对股骨延长 EFI 有显著的同时影响(p=0.021)。

讨论

本研究结果表明,在治疗获得性肢体长度差异时,使用 HA 涂层或非 HA 涂层钛 FIN 延长 EFI 无差异。联合技术可降低 EFI,避免严重并发症。非 HA 钉和 HA 涂层钉延长均可获得良好和优秀的结果。

证据水平

III 级(无随机对照的对照试验)前瞻性比较研究。

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