Hoensch H P
Acta Psychiatr Scand Suppl. 1986;329:66-8. doi: 10.1111/j.1600-0447.1986.tb10537.x.
Ethanol abuse has been shown to induce hepatic monooxygenase activity. In order to study the effect of chlormethiazole on the hepatic monooxygenase enzyme system, the O-deethylation of 7-ethoxycoumarin was studied. Chlormethiazole was found to inhibit ethanol-induced monooxygenase activity.