Department of Anatomy and Regenerative Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.
School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, UK.
J Anat. 2021 Nov;239(5):1221-1225. doi: 10.1111/joa.13549. Epub 2021 Oct 11.
Teaching and learning anatomy by using human cadaveric specimens has been a foundation of medical and biomedical teaching for hundreds of years. Therefore, the majority of institutions that teach topographical anatomy rely on body donation programmes to provide specimens for both undergraduate and postgraduate teaching of gross anatomy. The COVID-19 pandemic has posed an unprecedented challenge to anatomy teaching because of the suspension of donor acceptance at most institutions. This was largely due to concerns about the potential transmissibility of the SARS-CoV-2 virus and the absence of data about the ability of embalming solutions to neutralise the virus. Twenty embalming solutions commonly used in institutions in the United Kingdom and Ireland were tested for their ability to neutralise SARS-CoV-2, using an established cytotoxicity assay. All embalming solutions tested neutralised SARS-CoV-2, with the majority of solutions being effective at high-working dilutions. These results suggest that successful embalming with the tested solutions can neutralise the SARS-CoV-2 virus, thereby facilitating the safe resumption of body donation programmes and cadaveric anatomy teaching.
利用人体尸体标本进行解剖教学是数百年来医学和生物医学教学的基础。因此，大多数教授局部解剖学的机构都依赖于遗体捐赠计划，为本科和研究生的大体解剖教学提供标本。由于大多数机构暂停接受捐赠者，COVID-19 大流行给解剖教学带来了前所未有的挑战。这主要是由于担心 SARS-CoV-2 病毒的潜在传染性，以及没有关于防腐溶液中和病毒能力的数据。使用既定的细胞毒性测定法，对英国和爱尔兰机构中常用的 20 种防腐溶液进行了中和 SARS-CoV-2 的能力测试。所有测试的防腐溶液都能中和 SARS-CoV-2，大多数溶液在高工作稀释度下有效。这些结果表明，经测试的溶液能够成功地对 SARS-CoV-2 病毒进行防腐处理，从而能够安全地恢复遗体捐赠计划和尸体解剖教学。
