正常握力与未来高血压风险：一项前瞻性队列研究的结果。
Normalized handgrip strength and future risk of hypertension: findings from a prospective cohort study.
机构信息
National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol, Bristol, UK.
Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Learning & Research Building (Level 1), Southmead Hospital, Bristol, UK.
出版信息
Scand Cardiovasc J. 2021 Dec;55(6):336-339. doi: 10.1080/14017431.2021.1983206. Epub 2021 Oct 11.
Previous reports of an association between handgrip strength (HGS) and the risk of hypertension have utilized cross-sectional designs. We aimed to assess the prospective association between HGS and hypertension risk in a general population. Handgrip strength was assessed at baseline in 463 Finnish men and women aged 61-73 years. Handgrip strength was normalized (HGS/body weight). After 16 years median follow-up, 110 hypertension cases occurred. Comparing the extreme tertiles of normalized HGS, the multivariable adjusted hazard ratio (95% CI) for hypertension was 0.63 (0.38-1.04). Previous evidence of associations may have been driven by study design limitations such as lack of temporality.
先前有关握力（HGS）与高血压风险之间关联的报告均采用了横断面设计。我们旨在评估一般人群中 HGS 与高血压风险的前瞻性关联。在基线时，评估了 463 名年龄在 61-73 岁的芬兰男性和女性的握力。握力进行了标准化（HGS/体重）。在中位随访 16 年后，发生了 110 例高血压病例。比较标准化 HGS 的极端三分位值，高血压的多变量调整风险比（95%CI）为 0.63（0.38-1.04）。先前关联的证据可能是由研究设计局限性驱动的，例如缺乏时间性。
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