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居住安排与精神分裂症症状和功能的关联。

Associations of living arrangements with symptoms and functioning in schizophrenia.

机构信息

Research Division, Institute of Mental Health, Singapore, Singapore.

North Region & Department of Psychosis, Institute of Mental Health, Singapore, Singapore.

出版信息

BMC Psychiatry. 2021 Oct 11;21(1):497. doi: 10.1186/s12888-021-03488-5.

Abstract

BACKGROUND

Living arrangements and accommodation are closely related, but no study had concurrently investigated their associations with outcomes in schizophrenia. This study seeks to describe and compare socio-demographic, clinical and functioning profiles of people with schizophrenia in different living arrangements and accommodation, and to examine the associations of living arrangements and accommodation with symptomatic remission and functioning.

METHODS

Community dwelling outpatients with schizophrenia (n = 276) were inquired on living arrangements, accommodation, socio-demographics and assessed on the Positive and Negative Syndrome Scale (PANSS) and the Social and Occupational Functioning Scale (SOFAS). Socio-demographics, symptoms and functioning of outpatients in different living arrangements and accommodation were compared. Symptomatic remission was investigated using logistic regression with living arrangements, socio-demographics and clinical variables as independent variables. Functioning was investigated using multiple regression with the same set of independent variables and the addition of PANSS factors. The same analyses were conducted with accommodation as independent variable.

RESULTS

185 (67.03%) participants lived with family and 195 (70.65%) participants lived in owned accommodation. People living with their spouses had significantly higher SOFAS, lower PANSS Total and PANSS Positive than people living with family, independently, or in rehabilitation centres. They also had lower PANSS Negative than people living with family and a higher likelihood to have achieved symptomatic remission. Types of accommodation was not associated with symptoms, symptomatic remission, and functioning.

CONCLUSION

Living arrangements, but not types of accommodation, were associated with symptoms and functioning in schizophrenia. Family education and support is important to help maintain a conducive environment for people with schizophrenia. People living independently may need more support.

摘要

背景

生活安排和住所密切相关,但尚无研究同时调查它们与精神分裂症结局的关系。本研究旨在描述和比较不同生活安排和住所的精神分裂症患者的社会人口学、临床和功能特征,并探讨生活安排和住所与症状缓解和功能的关系。

方法

对 276 名居住在社区的精神分裂症门诊患者进行生活安排、住所、社会人口学等方面的调查,并采用阳性和阴性症状量表(PANSS)和社会和职业功能量表(SOFAS)进行评估。比较不同生活安排和住所的门诊患者的社会人口学、症状和功能。采用 logistic 回归分析以生活安排、社会人口学和临床变量为自变量,研究症状缓解。采用多元回归分析以相同的自变量集和 PANSS 因子的增加为自变量,研究功能。以住所为自变量进行相同的分析。

结果

185 名(67.03%)患者与家人同住,195 名(70.65%)患者居住在自有住所。与家人同住或住在康复中心的患者相比,与配偶同住的患者 SOFAS 更高,PANSS 总分和阳性症状评分更低,且更有可能达到症状缓解。住所类型与症状、症状缓解和功能无关。

结论

生活安排而非住所类型与精神分裂症的症状和功能有关。家庭教育和支持对于为精神分裂症患者营造有利环境很重要。独立生活的患者可能需要更多支持。

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First-episode psychosis and vocational outcomes: A predictive model.首发精神病与职业结局:预测模型。
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