Glants R M, Kachorovskiĭ B V, Turchin V L, Oborin A N, Chaplik V V
Biull Eksp Biol Med. 1986 Oct;102(10):412-4.
It has been shown that intraaortal prostaglandin E2 injection to dogs arrested acute renal failure of hemotransfusion genesis, which was expressed in normalization of minute and diurnal diuresis, glomerular filtration rate, tubular reabsorption, maximal tubular secretion, renal plasma flow, urea and creatinine levels. The data obtained serve as an experimental basis for prostaglandin E2 application in the treatment of acute renal failure.
已表明,向犬主动脉内注射前列腺素E2可阻止输血性急性肾衰竭,表现为每分钟和昼夜尿量、肾小球滤过率、肾小管重吸收、最大肾小管分泌、肾血浆流量、尿素和肌酐水平恢复正常。所获得的数据为前列腺素E2应用于治疗急性肾衰竭提供了实验依据。