中间葡萄球菌对氟喹诺酮类药物的耐药性

Fluoroquinolone resistance in Staphylococcus intermedius.

作者信息

Lloyd D H, Lamport A I, Noble W C, Howell S A

机构信息

Department of Small Animal Medicine and Surgery, Royal Veterinary College, London.

Department of Microbial Diseases, United Medical and Dental Schools, London.

出版信息

Vet Dermatol. 1999 Sep;10(3):249-251. doi: 10.1046/j.1365-3164.1999.00187.x.

DOI:10.1046/j.1365-3164.1999.00187.x

PMID:34644912

Abstract

Four canine isolates of S. intermedius resistant to enrofloxacin were isolated amongst a total of 429 screened. Two of these were shown to exhibit resistance also to marbofloxacin and ciprofloxacin. Whilst molecular studies have shown the mechanism of resistance to these quinolone antibiotics to be similar in a number of staphylococcal species, it was not possible to confirm this mechanism in Staphylococcus intermedius.

摘要

在总共筛查的429株犬源中间葡萄球菌中，分离出4株对恩诺沙星耐药的菌株。其中2株还显示出对马波沙星和环丙沙星耐药。虽然分子研究表明，许多葡萄球菌对这些喹诺酮类抗生素的耐药机制相似，但无法在中间葡萄球菌中证实这一机制。