Suppr超能文献

外周肺动脉的外科重建的远期结果。

Late outcomes of surgical reconstruction of peripheral pulmonary arteries.

机构信息

Department of Pediatric Cardiac Surgery, Prince Sultan Cardiac Center, Riyadh, Saudi Arabia.

Department of Cardiac Anesthesia, Prince Sultan Cardiac Center, Riyadh, Saudi Arabia.

出版信息

J Thorac Cardiovasc Surg. 2022 Apr;163(4):1448-1457.e6. doi: 10.1016/j.jtcvs.2021.07.057. Epub 2021 Sep 9.

Abstract

OBJECTIVE

The ideal management of peripheral pulmonary artery stenosis is still controversial. We adopted a primary surgical approach to this complex lesion with excellent early outcomes. In this study, we analyzed our late outcomes.

METHODS

We performed a retrospective review of 91 patients with biventricular anatomy who underwent peripheral pulmonary artery reconstruction from March 2008 to July 2020. Our surgical approach included either a single-stage complete repair through median sternotomy or a 2-stage repair through sternotomy/left thoracotomy, depending on the degree of distal involvement of the left pulmonary artery branches.

RESULTS

Median age was 26 months. Syndromic etiology was established in 54 patients (59.3%) versus nonsyndromic etiology in 37 patients (40.7%). Single-stage repair was achieved in 68 patients (74.7%). There were 2 (2.2%) in-hospital mortalities. The mean right ventricular to aortic systolic pressure ratio decreased from 1.07 ± 0.20 preoperatively to 0.32 ± 0.07 immediately postoperatively (P < .001), representing a 70.1% reduction. At 1-year postoperative catheterization, the mean right ventricular to aortic systolic pressure ratio was 0.28 ± 0.05 (P < .001 compared with immediately postoperative value). With a median follow-up of 68 months (IQR, 39-117.5 months), there was no late mortality after discharge. All patients were active and asymptomatic on the most recent follow-up. There were no early or late reinterventions on pulmonary arteries.

CONCLUSIONS

Late outcomes of surgical reconstruction of peripheral pulmonary arteries are excellent and durable in various pathologies (syndromic and nonsyndromic) with a significant reduction in right ventricular to aortic systolic pressure ratio, low mortality, and no reintervention.

摘要

目的

外周肺动脉狭窄的理想治疗方法仍存在争议。我们采用了一种主要的外科方法来治疗这种复杂的病变,取得了极好的早期结果。在本研究中,我们分析了晚期结果。

方法

我们对 2008 年 3 月至 2020 年 7 月期间接受双心室解剖结构的外周肺动脉重建的 91 例患者进行了回顾性分析。我们的手术方法包括通过正中胸骨切开术进行的单阶段完全修复,或根据左肺动脉分支的远端受累程度通过胸骨切开术/左开胸术进行的两阶段修复。

结果

中位年龄为 26 个月。综合征病因在 54 例患者(59.3%)中确立,而非综合征病因在 37 例患者(40.7%)中确立。68 例(74.7%)患者实现了单阶段修复。有 2 例(2.2%)院内死亡。右心室与主动脉收缩压比值从术前的 1.07±0.20 平均降至术后即刻的 0.32±0.07(P<0.001),降低了 70.1%。术后 1 年导管检查时,右心室与主动脉收缩压比值为 0.28±0.05(P<0.001 与术后即刻值比较)。中位随访 68 个月(IQR,39-117.5 个月),出院后无晚期死亡。最近一次随访时,所有患者均活跃且无症状。肺动脉无早期或晚期再干预。

结论

在外周肺动脉各种病变(综合征和非综合征)中,外科重建的晚期结果是出色且持久的,右心室与主动脉收缩压比值显著降低,死亡率低,且无再干预。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验