Department of Pediatric Cardiac Surgery, Prince Sultan Cardiac Center, Riyadh, Saudi Arabia.
Department of Cardiac Anesthesia, Prince Sultan Cardiac Center, Riyadh, Saudi Arabia.
J Thorac Cardiovasc Surg. 2022 Apr;163(4):1448-1457.e6. doi: 10.1016/j.jtcvs.2021.07.057. Epub 2021 Sep 9.
The ideal management of peripheral pulmonary artery stenosis is still controversial. We adopted a primary surgical approach to this complex lesion with excellent early outcomes. In this study, we analyzed our late outcomes.
We performed a retrospective review of 91 patients with biventricular anatomy who underwent peripheral pulmonary artery reconstruction from March 2008 to July 2020. Our surgical approach included either a single-stage complete repair through median sternotomy or a 2-stage repair through sternotomy/left thoracotomy, depending on the degree of distal involvement of the left pulmonary artery branches.
Median age was 26 months. Syndromic etiology was established in 54 patients (59.3%) versus nonsyndromic etiology in 37 patients (40.7%). Single-stage repair was achieved in 68 patients (74.7%). There were 2 (2.2%) in-hospital mortalities. The mean right ventricular to aortic systolic pressure ratio decreased from 1.07 ± 0.20 preoperatively to 0.32 ± 0.07 immediately postoperatively (P < .001), representing a 70.1% reduction. At 1-year postoperative catheterization, the mean right ventricular to aortic systolic pressure ratio was 0.28 ± 0.05 (P < .001 compared with immediately postoperative value). With a median follow-up of 68 months (IQR, 39-117.5 months), there was no late mortality after discharge. All patients were active and asymptomatic on the most recent follow-up. There were no early or late reinterventions on pulmonary arteries.
Late outcomes of surgical reconstruction of peripheral pulmonary arteries are excellent and durable in various pathologies (syndromic and nonsyndromic) with a significant reduction in right ventricular to aortic systolic pressure ratio, low mortality, and no reintervention.
外周肺动脉狭窄的理想治疗方法仍存在争议。我们采用了一种主要的外科方法来治疗这种复杂的病变,取得了极好的早期结果。在本研究中,我们分析了晚期结果。
我们对 2008 年 3 月至 2020 年 7 月期间接受双心室解剖结构的外周肺动脉重建的 91 例患者进行了回顾性分析。我们的手术方法包括通过正中胸骨切开术进行的单阶段完全修复,或根据左肺动脉分支的远端受累程度通过胸骨切开术/左开胸术进行的两阶段修复。
中位年龄为 26 个月。综合征病因在 54 例患者(59.3%)中确立,而非综合征病因在 37 例患者(40.7%)中确立。68 例(74.7%)患者实现了单阶段修复。有 2 例(2.2%)院内死亡。右心室与主动脉收缩压比值从术前的 1.07±0.20 平均降至术后即刻的 0.32±0.07(P<0.001),降低了 70.1%。术后 1 年导管检查时,右心室与主动脉收缩压比值为 0.28±0.05(P<0.001 与术后即刻值比较)。中位随访 68 个月(IQR,39-117.5 个月),出院后无晚期死亡。最近一次随访时,所有患者均活跃且无症状。肺动脉无早期或晚期再干预。
在外周肺动脉各种病变(综合征和非综合征)中,外科重建的晚期结果是出色且持久的,右心室与主动脉收缩压比值显著降低,死亡率低,且无再干预。