乳腺错构瘤:临床、放射学及组织病理学评估

Breast Hamartoma: Clinical, Radiological, and Histopathological Evaluation.

作者信息

Tazeoğlu Deniz, Dağ Ahmet, Arslan Bilal, Berkeşoğlu Mustafa

机构信息

Department of General Surgery, Faculty of Medicine Mersin University, Mersin, Turkey.

出版信息

Eur J Breast Health. 2021 Oct 4;17(4):328-332. doi: 10.4274/ejbh.galenos.2021.2021-3-6. eCollection 2021 Oct.

Abstract

OBJECTIVE

Breast hamartomas are rare, benign, and slow-growing breast tumors that can be definitively diagnosed by combining the results of clinical, radiological, and histopathological examination. This study aimed to evaluate the clinical, radiological, and histopathological features of hamartomas and summarize our clinical approach to hamartomas.

MATERIALS AND METHODS

Patients diagnosed with breast hamartoma between 2010 and 2020 in our clinic were retrospectively analyzed. Demographic information, clinical examination, radiological findings, histopathological features, changes during follow-up, and follow-up data were obtained and analyzed.

RESULTS

Of the 1,429 patients operated on in our clinic for benign breast diseases between January 2010 and March 2020, 39 (2.7%) were diagnosed with breast hamartomas with histopathological examination. All patients were women with a median age of 37 (19-62) years. Most of the patients (64%) were in the premenopausal period. Radiological examinations were conducted using mammography (66%), breast ultrasonography (100%), and breast magnetic resonance imaging (48%). Biopsy was performed in 14 preoperative patients, and nine (64%) patients were diagnosed with hamartoma. All patients were operated on; 37 patients underwent a lumpectomy, and two had a mastectomy. No patients had hamartoma recurrence during an average follow-up period of 39 months.

CONCLUSION

Hamartomas are similar to other benign breast pathologies. Definitive diagnosis can be achieved by combining the results of clinical, radiological, and histopathological examination. Given its similar composition to normal breast tissue, hamartoma has a low rate of malignancy. Definitive diagnosis and appropriate surgical treatment are required.

摘要

目的

乳腺错构瘤是一种罕见的、良性的、生长缓慢的乳腺肿瘤,可通过结合临床、影像学和组织病理学检查结果进行明确诊断。本研究旨在评估错构瘤的临床、影像学和组织病理学特征,并总结我们对错构瘤的临床处理方法。

材料与方法

回顾性分析2010年至2020年在我院诊断为乳腺错构瘤的患者。获取并分析人口统计学信息、临床检查、影像学表现、组织病理学特征、随访期间的变化以及随访数据。

结果

2010年1月至2020年3月在我院因良性乳腺疾病接受手术的1429例患者中,39例(2.7%)经组织病理学检查诊断为乳腺错构瘤。所有患者均为女性,中位年龄37(19 - 62)岁。大多数患者(64%)处于绝经前期。影像学检查采用乳腺钼靶(66%)、乳腺超声(100%)和乳腺磁共振成像(48%)。14例术前患者进行了活检,其中9例(64%)诊断为错构瘤。所有患者均接受了手术;37例行肿块切除术,2例行乳房切除术。在平均39个月的随访期内,无患者出现错构瘤复发。

结论

错构瘤与其他良性乳腺病变相似。通过结合临床、影像学和组织病理学检查结果可实现明确诊断。鉴于其与正常乳腺组织的组成相似,错构瘤的恶性率较低。需要进行明确诊断和适当的手术治疗。

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