Department of Medicine, University of Bisha, Bisha, Saudi Arabia.
King Abdullah Hospital, Bisha, Saudi Arabia.
Niger J Clin Pract. 2021 Oct;24(10):1423-1429. doi: 10.4103/njcp.njcp_459_20.
Despite the reports of carpal tunnel syndrome (CTS) being commonplace in Saudi Arabia, there is scarcity of cross-sectional or prospective studies detailing the profile of nerve conduction study (NCS) findings in patients with CTS.
The study aimed to evaluate the neurophysiologic profile of CTS with the view to finding the determinant of abnormal findings in clinically diagnosed cases of CTS in a population of Saudis.
Nerve conduction study was performed on consecutive patients with clinically diagnosed CTS. Median sensory, ulnar sensory, radial sensory median motor and ulnar motor nerves were assessed. The nerve conduction parameters measured were median and ulnar sensory peak latency, amplitude and velocity. Median conduction velocity, distal latency, and amplitude were also measured. Comparative median-ulnar and median-ulnar-digit 4 studies were done and the severity of CTS was determined. Data was analyzed using STATA software version 12.
A total of 152 patients, comprising 59 males and 93 females (mean age of 42.7 years) with clinically diagnosed CTS were seen during the study period. About 72.4% patients had numbness and paresthesia in the affected fingers, 66.5% had pain in the hands, and 10.5% had weakness in the affected hands. Majority of the patients (62%) had bilateral clinical features. Carpal tunnel syndrome was confirmed with NCS in 84 (55.26%) patients. Presence of weakness in the affected hand, positive Phalen' sign, and positive Tinel's sign in patients appear to predict [6.1 (1.2-30.7), 3.9 (1.2-30.2), and 4.9 (1.4-17.0) respectively] abnormal NCS findings after adjustment for age, gender and the presence of DM.
The study revealed that over half of the patients with CTS had NCS/ Electromyography (EMG) abnormalities. Presence of hand muscles weakness, positive Phalen and Tinel's signs predict abnormal findings on NCS/EMG in patients with CTS.
尽管沙特阿拉伯有大量腕管综合征（CTS）的报告，但很少有横断面或前瞻性研究详细描述 CTS 患者神经传导研究（NCS）结果的特征。
本研究旨在评估 CTS 的神经生理特征，以期发现沙特人群中临床诊断为 CTS 的病例中异常发现的决定因素。
对连续的临床诊断为 CTS 的患者进行神经传导研究。评估正中感觉、尺神经感觉、桡神经感觉、正中运动和尺神经运动神经。测量的神经传导参数包括正中神经和尺神经感觉峰潜伏期、幅度和速度。还测量了正中神经传导速度、远端潜伏期和幅度。进行了正中神经-尺神经和正中神经-第四指比较研究，并确定了 CTS 的严重程度。使用 STATA 软件版本 12 进行数据分析。
在研究期间，共观察到 152 名患者，其中男性 59 名，女性 93 名（平均年龄 42.7 岁），患有临床诊断为 CTS。约 72.4%的患者出现受累手指麻木和感觉异常，66.5%的患者手部疼痛，10.5%的患者手部无力。大多数患者（62%）有双侧临床特征。152 名患者中有 84 名（55.26%）通过 NCS 确诊为 CTS。在调整年龄、性别和 DM 存在的情况下，患者手部无力、Phalen 征阳性和 Tinel 征阳性似乎预测 NCS 异常发现的概率分别为[6.1（1.2-30.7）、3.9（1.2-30.2）和 4.9（1.4-17.0）]。
本研究表明，超过一半的 CTS 患者存在 NCS/肌电图（EMG）异常。手部肌肉无力、Phalen 征和 Tinel 征阳性预测 CTS 患者 NCS/EMG 异常发现。
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