Choudhary Soumitra, Bhatia Surita R
Department of Chemical Engineering, University of Massachusetts Amherst, Amherst, MA 01003 United States.
Department of Chemical Engineering, University of Massachusetts Amherst, Amherst, MA 01003 United States.
Carbohydr Polym. 2012 Jan 4;87(1):524-530. doi: 10.1016/j.carbpol.2011.08.025. Epub 2011 Aug 17.
The effect of hydrophobic modification on the mechanical and structural characteristics of hydrophobically modified alginate (HMA) solutions and hydrogels were evaluated. The HMA systems consisted of alkyl chains, C, grafted onto alginate backbones. With an increase in degree of substitution of hydrophobic tails, the association became stronger in solution, but same was not true for gels. The contribution of ionic crosslinking was found to be the dominant factor in determining the mechanical strength of hydrogels. Rheological measurements of 2wt% HMA gels reveal formation of a strongly crosslinked network with an elastic modulus close to 100kPa. Small-angle X-ray scattering (SAXS) experiments indicate that HMA assembles into a disordered structure with regions rich in the hydrophobic domain surrounded by a crosslinked hydrophilic network.
评估了疏水改性对疏水改性海藻酸盐（HMA）溶液和水凝胶的力学和结构特性的影响。HMA体系由接枝到海藻酸主链上的烷基链C组成。随着疏水尾取代度的增加，溶液中的缔合作用增强，但凝胶并非如此。发现离子交联的作用是决定水凝胶力学强度的主要因素。对2wt% HMA凝胶的流变学测量表明形成了一个强交联网络，其弹性模量接近100kPa。小角X射线散射（SAXS）实验表明，HMA组装成一种无序结构，其中富含疏水区域，周围是交联的亲水网络。
