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皮肤科门诊中皮质类固醇类药物的不当使用。

Inappropriate Use of Topical Corticosteroides in the Dermatology Outpatient.

机构信息

Department of Dermatology and Venereology, Clinical Hospital Mostar, Mostar, Bosnia and Herzegovina.

出版信息

Psychiatr Danub. 2021 Sep;33(Suppl 10):71-75.

Abstract

INTRODUCTION

Topical corticosteroids are group of drugs which have anti-in?ammatory, immuno-suppressive, anti-proliferative and vasoconstrictive effects and are among the most commonly prescribed medication, important and efficacious for management of various dermatological disorders. Strict implementation of the existing regulations is the need of the hour to prevent their widespread abuse. Aim of the study was to investigate the usage of topical corticosteroids therapy with the recipe of a doctor and without it.

SUBJECTS AND METHODS

The subjects were patients who visited Pharmacies in Mostar from April to July 2020 and were buying topical corticosteroids with or without a recipe or medical report from the doctor. 80 subjects completed a questionnaire themselves included: the way of buying a topical corticosteroids, the information about using topical corticosteroids earlier, the information about subject's visits to the doctor; the length of time using topical corticosteroids, the type of topical corticosteroids used, the part of body the topical corticosteroids was applied on.

RESULTS

A total of 80 subjects were treated in the observed period, 58.8% were female. 72.5% subjects had already used local corticosteroids, 62.50% purchased the drug at the recommendation of the pharmacist, 66.30% had no recent diagnosis or no diagnosed disease at all, 21.25% used the drug for more than a month, the most often purchased one was moderate potent local corticosteroid Betamethasone diproprionate 0.05%. Most commonly subjects applied local corticosteroids on arms (50%).

CONCLUSION

Strict regulations regarding only prescription-based dispensing of local corticosteroids must be put into practice. This will hopefully bring down both the extremes of ever increasing cases of steroid-induced dermatoses in everyday dermatology practise on one hand and the irrational fears of using TCs in well justified indications on the other.

摘要

简介

局部皮质类固醇是一组具有抗炎、免疫抑制、抗增殖和血管收缩作用的药物,是最常开的药物之一,对于治疗各种皮肤病非常重要和有效。严格执行现有规定是防止它们广泛滥用的当务之急。本研究的目的是调查在有处方和没有处方的情况下使用局部皮质类固醇治疗的情况。

受试者和方法

受试者是 2020 年 4 月至 7 月期间在莫斯塔尔药房购买局部皮质类固醇的患者,他们购买的药物有的有处方或医生的医疗报告,有的没有。80 名受试者自己完成了一份问卷,包括:购买局部皮质类固醇的方式、以前使用局部皮质类固醇的信息、受试者就诊的信息;使用局部皮质类固醇的时间长度、使用的局部皮质类固醇类型、局部皮质类固醇应用的身体部位。

结果

在观察期间共治疗了 80 名受试者,其中 58.8%为女性。72.5%的受试者以前使用过局部皮质类固醇,62.50%的受试者是根据药剂师的建议购买的药物,66.30%的受试者最近没有诊断或根本没有诊断出任何疾病,21.25%的受试者使用药物超过一个月,最常购买的是中度强效局部皮质类固醇倍他米松二丙酸酯 0.05%。最常见的是将局部皮质类固醇应用于手臂(50%)。

结论

必须严格执行只有凭处方才能配发局部皮质类固醇的规定。这有望一方面减少日常皮肤科实践中皮质类固醇诱导的皮肤病病例不断增加的极端情况,另一方面也减少了在合理指征下使用 TCs 的不合理恐惧。

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