Wishart P K, Hitchings R A
Trans Ophthalmol Soc U K (1962). 1986;105 ( Pt 5):521-40.
A prospective, randomised study compared Neodymium:Yttrium Aluminium Garnet (Nd:YAG) and dye laser iridotomy in 100 eyes of 61 patients for the relief of pupil block glaucoma. Nd:YAG laser iridotomy was accompanied by less severe complications at the time of iridotomy--failure to produce full-thickness iridotomy, post-laser hypertensive response, bleeding, dissemination of pigment throughout the anterior chamber and posterior synechiae formation--than the dye laser. Nd:YAG laser iridotomy initially achieved relief of pupil block in all the eyes undergoing this procedure. However, the overall success rate of Nd:YAG iridotomies over the 3 months' follow-up period fell to 78 per cent due to inability of small iridotomies to relieve pupil block (4 eyes), and closure of iridotomies by iris pigment epithelial proliferation (3 eyes) and/or stromal healing (3 eyes). In patients with narrow angle glaucoma severe, and in cases prolonged elevations of intraocular pressure occurred following iridotomy with both lasers. Significant lens damage occurred in 5 eyes following dye laser iridotomy.
钇铝石榴石(Nd:YAG)激光虹膜切开术和染料激光虹膜切开术对61例患者100只眼睛瞳孔阻滞性青光眼的缓解效果。Nd:YAG激光虹膜切开术在虹膜切开时的并发症(未能形成全层虹膜切开、激光后高血压反应、出血、色素播散至整个前房以及后粘连形成)比染料激光轻。Nd:YAG激光虹膜切开术最初使所有接受该手术的眼睛的瞳孔阻滞得到缓解。然而,在3个月的随访期内,Nd:YAG虹膜切开术的总体成功率降至78%,原因是小的虹膜切开术无法缓解瞳孔阻滞(4只眼),以及虹膜色素上皮增生(3只眼)和/或基质愈合(3只眼)导致虹膜切开术闭合。在严重窄角型青光眼患者中,以及在两种激光虹膜切开术后眼压长期升高的病例中,染料激光虹膜切开术后有5只眼发生了明显的晶状体损伤。