Hospital Universitari Arnau de Vilanova, 25006 Lleida, España.
Institut de Recerca Biomèdica de Lleida. Universitat de Lleida, Lleida, España.
Rev Neurol. 2021 Nov 1;73(9):321-336. doi: 10.33588/rn.7309.2021138.
Cerebrovascular disease (CVD) is responsible for the majority of disability-adjusted life years and is a leading cause of mortality. This impact justifies having up-to-date data on its incidence.
We conducted a systematic review of the studies published since 2010 that provided information on the crude incidence rate (CIR) and adjusted incidence rate of CVD during the second decade of the 21st century.
Thirty-five articles were identified. Twenty-eight provided information on the overall incidence of CVD, 19 on the incidence of ischaemic stroke (IS), 19 on the incidence of haemorrhagic stroke (HS) and 10 on the incidence of subarachnoid haemorrhage (SAH). The incidence was heterogeneous across countries. Thus, the median CIR was 149.5 - confidence interval 95% (CI 95%): 122-256 - cases per 100,000 inhabitants for CVD; 155 (CI 95%: 95.6-246.12) for SI; 29 (CI 95%: 19-43) for HS; and 6.5 (CI 95%: 4.8-13.5) for SAH. The incidence for both CVD and IS and HS was higher in men than in women in most studies, with the exception of some Asian, European and North American studies. The majority of studies showed a decreasing or stabilising trend in incidence, with the exception of studies conducted in China, Singapore, France and Australia.
There are few studies that analyse the incidence of CVD and even fewer that analyse its evolution. The overall median remains high, although the figures are heterogeneous across studies. Worldwide the trend is towards its decrease, and there are geographical areas, especially in Asia, with an alarming upward trend.
脑血管疾病（CVD）是导致大多数失能调整生命年的主要原因，也是导致死亡的主要原因。这一影响证明了我们需要掌握其发病率的最新数据。
我们对 2010 年以来发表的、提供 21 世纪第二个十年期间 CVD 粗发病率（CIR）和调整发病率信息的研究进行了系统回顾。
共确定了 35 篇文章。其中 28 篇提供了 CVD 总体发病率的信息，19 篇提供了缺血性卒中（IS）发病率的信息，19 篇提供了出血性卒中（HS）发病率的信息，10 篇提供了蛛网膜下腔出血（SAH）发病率的信息。各国的发病率存在差异。因此，CVD 的 CIR 中位数为 149.5（95%CI95%：122-256）/100000 人，IS 为 155（95%CI95%：95.6-246.12）/100000 人，HS 为 29（95%CI95%：19-43）/100000 人，SAH 为 6.5（95%CI95%：4.8-13.5）/100000 人。在大多数研究中，男性的 CVD、IS 和 HS 发病率均高于女性，但亚洲、欧洲和北美部分研究除外。大多数研究显示发病率呈下降或稳定趋势，中国、新加坡、法国和澳大利亚的研究除外。
分析 CVD 发病率的研究较少，分析其演变的研究更少。虽然各研究之间数据存在差异，但总体中位数仍然较高。全球范围内发病率呈下降趋势，但亚洲部分地区发病率上升令人担忧。
