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18F-FDG摄取增加的肺空洞提示胸段子宫内膜异位症:一例报告

Pulmonary cavitations with increased 18F-FDG uptake revealing a thoracic endometriosis: A case report.

作者信息

Mulette Pauline, Jacquet Amaury, Durlach Anne, Papathanassiou Dimitri, Lalire Paul, Graesslin Olivier, Delepine Gonzague, Dury Sandra, Dormoy Valérian, Perotin Jeanne-Marie, Lebargy François, Deslée Gaëtan, Launois Claire

机构信息

Department of Respiratory Diseases, Reims University Hospital, France.

Department of Pathology, Reims University Hospital, France.

出版信息

Medicine (Baltimore). 2021 Oct 22;100(42):e27550. doi: 10.1097/MD.0000000000027550.

Abstract

RATIONALE

Thoracic endometriosis is a rare disorder that can involve airways, pleura and lung parenchyma. It is the most frequent form of extra-abdominopelvic endometriosis. Multiple lung cavitations are a rare feature of thoracic endometriosis.

PATIENT CONCERNS

A 46-year-old woman was referred to our hospital after incidental finding of multiple pulmonary cavitations with surrounding areas of ground glass opacity on a thoraco-abdominal computed tomography-scan performed for abdominal pain. Retrospectively, the patient also reported mild hemoptysis occurring 4 months ago.

DIAGNOSES

Positron emission tomography-computed tomography scan revealed moderate and homogeneous [18F] fluoro-2-deoxy-D-glucose (18F-FDG) uptake in pulmonary cavitations (maximum standardized uptake value 5.7). The diagnosis of thoracic endometriosis was confirmed by histological examination of surgical resection of a left lower lobe cavitation.

INTERVENTIONS AND OUTCOME

Gonadotropin-releasing hormone analogues associated with add-back therapy was started. Four months after initiating pharmacological treatment, the chest computed tomography-scan showed a dramatic decrease in lung cavitations size.

LESSONS

Thoracic endometriosis is a rare disorder requiring a multidisciplinary management including gynaecologist, pulmonologist, radiologist, nuclear physician, pathologist and thoracic surgeon for early diagnosis and treatment. Our case report highlights that an increased 18F-FDG uptake can be found in thoracic endometriosis syndrome presenting as multiple lung cavitations.

摘要

原理

胸段子宫内膜异位症是一种罕见的疾病,可累及气道、胸膜和肺实质。它是腹盆腔外子宫内膜异位症最常见的形式。多发性肺空洞是胸段子宫内膜异位症的罕见特征。

患者情况

一名46岁女性因腹痛行胸腹计算机断层扫描时偶然发现多个肺空洞及周围磨玻璃样混浊区,随后被转诊至我院。回顾性分析,患者还报告4个月前出现轻度咯血。

诊断

正电子发射断层扫描-计算机断层扫描显示肺空洞内[18F]氟-2-脱氧-D-葡萄糖(18F-FDG)摄取中度且均匀(最大标准化摄取值5.7)。通过对左下叶空洞手术切除标本进行组织学检查,确诊为胸段子宫内膜异位症。

干预措施及结果

开始使用促性腺激素释放激素类似物联合反向添加疗法。开始药物治疗4个月后,胸部计算机断层扫描显示肺空洞大小显著减小。

经验教训

胸段子宫内膜异位症是一种罕见疾病,需要多学科管理,包括妇科医生、肺科医生、放射科医生、核医学医生、病理科医生和胸外科医生,以便早期诊断和治疗。我们的病例报告强调,在表现为多发性肺空洞的胸段子宫内膜异位症综合征中可发现18F-FDG摄取增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a42d/8542117/f324fe5f3301/medi-100-e27550-g001.jpg

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引用本文的文献

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Advances in Imaging for Assessing Pelvic Endometriosis.
Diagnostics (Basel). 2022 Nov 26;12(12):2960. doi: 10.3390/diagnostics12122960.

本文引用的文献

1
Thoracic Endometriosis Syndrome: A Review of Diagnosis and Management.
JSLS. 2019 Jul-Sep;23(3). doi: 10.4293/JSLS.2019.00029.
2
Clinical Management of Endometriosis.
Obstet Gynecol. 2018 Mar;131(3):557-571. doi: 10.1097/AOG.0000000000002469.
3
Thoracic endometriosis: clinicopathologic updates and issues about 18 cases from a tertiary referring center.
Ann Diagn Pathol. 2015 Oct;19(5):320-5. doi: 10.1016/j.anndiagpath.2015.07.001. Epub 2015 Jul 8.
4
Clinical features of thoracic endometriosis: A single center analysis.
Obstet Gynecol Sci. 2015 May;58(3):223-31. doi: 10.5468/ogs.2015.58.3.223. Epub 2015 May 19.
5
Increased 18F-FDG uptake of widespread endometriosis mimicking ovarian malignancy.
Clin Nucl Med. 2015 Feb;40(2):186-8. doi: 10.1097/RLU.0000000000000657.
6
Thoracic endometriosis syndrome: case report and review of the literature.
Perm J. 2014 Summer;18(3):61-5. doi: 10.7812/TPP/13-154.
7
Endometriosis.
BMJ. 2014 Mar 19;348:g1752. doi: 10.1136/bmj.g1752.
8
Evaluation of 18FDG PET-CT in the diagnosis of endometriosis: a prospective study.
Reprod Sci. 2011 Jun;18(6):540-4. doi: 10.1177/1933719110392060. Epub 2011 Feb 1.
10
Extragenital endometriosis.
Clin Obstet Gynecol. 2010 Jun;53(2):449-66. doi: 10.1097/GRF.0b013e3181e0ea6e.

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