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英国一家地区综合医院用于腹水管理的留置腹膜导管:一项队列研究。

Indwelling Peritoneal Catheter for Ascites Management in a UK District General Hospital: A Cohort Study.

作者信息

Jackson Karl, Frew Katie, Johnston Robert, Coleman Joanna, Armstrong Leonie, Aujayeb Avinash

机构信息

Respiratory Department, Northumbria Healthcare NHS Foundation Trust, Cramlington NE23 6NZ, UK.

Palliative Care Department, Northumbria Healthcare NHS Foundation Trust, Cramlington NE23 6NZ, UK.

出版信息

Healthcare (Basel). 2021 Sep 24;9(10):1254. doi: 10.3390/healthcare9101254.

Abstract

BACKGROUND

There is no national or local guidance for management of malignancy-related ascites (MRA). Modalities can include large volume paracentesis (LVP) and indwelling peritoneal catheter (IPeC) insertion.

OBJECTIVES

We set up a local IPeC service and performed a retrospective review with local ethical (Caldicott) approval. We hypothesized that an IPeC service would reduce inpatient stay related to MRA management, would be acceptable to patients, and have minimal complications.

METHODS

Notes of all patients requiring IPeC insertion were reviewed. Descriptive statistical methodology was applied with continuous data presented as mean (standard deviation (SD); range) and categorical variables as frequencies or percentages. Integrated Palliative Care Outcome Scale (IPOS) scores were collected for IPeC patients.

RESULTS

Thirty-four patients were identified. They were predominantly female, with a mean age of 66.6 years and a wide range of cancer diagnoses. Twenty-nine were inserted as day case procedures, and 31 had preceding paracenteses (mean 2). Main complications were leakage (6(17%)), peritonitis (2(5.8%)), and skin infection (1(3%)). IPOS scores showed consistent improvement in symptoms.

CONCLUSIONS

An IPeC service for malignant-related ascites is acceptable to patients and is associated with manageable complication rates. We present the development of our service and hope for widespread application.

摘要

背景

目前尚无关于恶性肿瘤相关腹水(MRA)管理的国家或地方指南。治疗方式可包括大量腹腔穿刺放液(LVP)和置入腹腔留置导管(IPeC)。

目的

我们设立了一项本地IPeC服务,并在获得当地伦理(考迪科特)批准后进行了回顾性研究。我们假设IPeC服务将减少与MRA管理相关的住院时间,患者会接受该服务,且并发症极少。

方法

对所有需要置入IPeC的患者的病历进行了回顾。采用描述性统计方法,连续数据以均值(标准差(SD);范围)呈现,分类变量以频率或百分比呈现。收集了IPeC患者的综合姑息治疗结果量表(IPOS)评分。

结果

共确定了34例患者。他们以女性为主,平均年龄66.6岁,癌症诊断范围广泛。29例作为日间手术置入导管,31例之前进行过腹腔穿刺放液(平均2次)。主要并发症为渗漏(6例(17%))、腹膜炎(2例(5.8%))和皮肤感染(1例(3%))。IPOS评分显示症状持续改善。

结论

恶性肿瘤相关腹水的IPeC服务患者可接受,且并发症发生率可控。我们介绍了我们服务的开展情况,并希望其能得到广泛应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b46/8536105/e914a33e2859/healthcare-09-01254-g001.jpg

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