Department of Clinical Therapeutics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Am J Hematol. 2022 Jan 1;97(1):119-128. doi: 10.1002/ajh.26384. Epub 2021 Nov 8.
Coronavirus disease 19 (COVID-19) is considered a multisystemic disease. Several studies have reported persistent symptoms or late-onset complications after acute COVID-19, including post-COVID-19 hematological disorders. COVID-19-induced coagulopathy, an immunothrombotic state, has been linked to thromboembolic and hemorrhagic events. Late-onset thrombocytopenia related to immune system dysregulation has also been reported as a rare manifestation post COVID-19. Close monitoring of laboratory dynamics is considered essential to identify timely abnormal values that need further investigation, providing supportive care whenever indicated. The role of hematologists is essential in terms of the multidisciplinary approach of long COVID-19. This review summarizes all the available evidence on post-acute COVID-19 hematological complications.
新型冠状病毒病(COVID-19)被认为是一种多系统疾病。多项研究报告称,急性 COVID-19 后存在持续症状或迟发性并发症,包括 COVID-19 后血液学疾病。COVID-19 引起的凝血功能障碍,即免疫性血栓状态,与血栓栓塞和出血事件有关。COVID-19 后也有报道称,免疫系统失调导致的迟发性血小板减少症是一种罕见表现。密切监测实验室动态被认为是识别需要进一步检查的及时异常值的重要手段,必要时提供支持性护理。在 COVID-19 后多学科治疗中,血液学家的作用至关重要。本综述总结了 COVID-19 后急性期血液学并发症的所有现有证据。