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德克萨斯州医院因症状性颈动脉狭窄行指数住院手术的性别、种族和民族差异。

Gender, racial and ethnic disparities in index hospitalization operations for symptomatic carotid stenosis in Texas hospitals.

机构信息

Division of Vascular Surgery and Endovascular Therapy, Michael E. DeBakey Department of Surgery, Baylor College of Medicine / Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX.

Division of Vascular Surgery and Endovascular Therapy, Michael E. DeBakey Department of Surgery, Baylor College of Medicine / Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX.

出版信息

Ann Vasc Surg. 2022 Mar;80:152-157. doi: 10.1016/j.avsg.2021.08.039. Epub 2021 Oct 20.

Abstract

BACKGROUND

Recent literature and societal recommendations support early revascularization of symptomatic carotid patients over the traditional six-week period. Nonetheless, the timing of these interventions can vary widely among populations. The goal of this study is to identify any factors influencing carotid revascularization during the index hospitalization for patients with symptomatic disease.

METHODS

The Texas Department of State Health Services database was queried to identify all patients > 45 years old admitted to nonfederal Texas Hospitals between 2009 to 2013 with an admission diagnosis of carotid artery stenosis and either transient ischemic attack (TIA), cerebrovascular accident (CVA), or amaurosis fugax. Diagnoses codes and demographic data were also used to adjust for clinical, social, and demographic factors (including area of residence and treatment). Descriptive statistics and multivariable logistic regression were used to identify significant factors for index admission revascularization.

RESULTS

A total of 29,046 symptomatic patients were identified among the 153,484 patients who had an eligible admission diagnosis. This included 16,244 (55.9%) males and 12,802 (44.1%) females. Only 4,594 (15.8%) patients were revascularized during the index hospitalization. The majority of these patients presented with amaurosis (OR 5.58; 95% CI 4.84-6.44) instead of CVAs (OR 0.48; 95% CI 0.45-0.51) or TIAs . Adjusting for hospital volume, insurance coverage, residence, and other clinical factors, rates of index admission carotid intervention remained significantly lower for women (OR 0.85; 95% CI 0.79-0.91), persons categorized as black (OR 0.60; 95% CI 0.53-0.69), and persons categorized as Hispanic (OR 0.77; 95% CI 0.70-0.86).

CONCLUSIONS

Gender, race and ethnicity appear to correlate with rates of carotid intervention at index hospitalization despite thorough risk adjustment for clinical, social and demographic factors. Efforts should be directed towards reducing these disparities.

摘要

背景

近期文献和社会建议支持对有症状的颈动脉患者在传统的六周内进行早期血运重建。然而,这些干预措施的时机在不同人群中差异很大。本研究的目的是确定影响有症状疾病患者指数住院期间颈动脉血运重建的任何因素。

方法

德克萨斯州州立卫生服务部数据库被查询,以确定 2009 年至 2013 年期间在非联邦德克萨斯州医院住院的年龄>45 岁的所有患者,其入院诊断为颈动脉狭窄,并有短暂性脑缺血发作(TIA)、脑血管意外(CVA)或一过性黑矇。诊断代码和人口统计学数据也用于调整临床、社会和人口统计学因素(包括居住区域和治疗)。使用描述性统计和多变量逻辑回归来确定指数入院血运重建的显著因素。

结果

在 153484 例符合条件的入院诊断患者中,共确定了 29046 例有症状患者。这包括 16244 名(55.9%)男性和 12802 名(44.1%)女性。只有 4594 名(15.8%)患者在指数住院期间进行了血运重建。这些患者中大多数是由于一过性黑矇(OR 5.58;95% CI 4.84-6.44)而不是 CVA(OR 0.48;95% CI 0.45-0.51)或 TIA 而就诊。调整医院容量、保险覆盖范围、居住地和其他临床因素后,女性(OR 0.85;95% CI 0.79-0.91)、黑人(OR 0.60;95% CI 0.53-0.69)和西班牙裔(OR 0.77;95% CI 0.70-0.86)患者的指数入院颈动脉介入治疗率仍然显著较低。

结论

尽管对临床、社会和人口统计学因素进行了全面的风险调整,但性别、种族和民族似乎与指数住院期间的颈动脉介入治疗率相关。应努力减少这些差异。

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