Department of Ophthalmology, Stanford University School of Medicine, Palo Alto, California, USA.
Department of Ophthalmology, Chonnam National University Medical School and Hospital, Gwangju, Republic of Korea.
Acta Ophthalmol. 2022 Sep;100(6):e1216-e1222. doi: 10.1111/aos.15053. Epub 2021 Oct 24.
To investigate types of surgeries performed to treat a presumed congenital superior oblique palsy (SOP) and the reoperation rate.
This was a population-based retrospective cohort study using claims data from the United States. Patients who underwent strabismus surgery for a presumed congenital SOP with ≥ 3 months of continuous enrolment after the initial surgery were included. We investigated age, surgical methods and the time interval between the initial surgery and reoperation. The hazard ratios for reoperation were estimated according to the surgical methods using Cox regression analysis.
A total of 3,998 patients underwent surgery for presumed congenital SOP; 2,981 (74.6%) on only one vertical muscle (excluding superior oblique). Reoperation was performed on 427 patients (10.7%). Compared to patients who underwent unilateral surgery on one vertical muscle (excluding superior oblique muscle), patients who underwent surgery that included the superior oblique muscle (unilateral 2.08; 95% CI, 1.61-2.67, p < 0.001; bilateral 2.44; 95% CI, 1.40-4.28, p = 0.002) and two or more vertical muscles (excluding the superior oblique muscle) (unilateral 2.99; 95% CI, 2.00-4.49, p < 0.001; bilateral 1.68; 95% CI, 1.23-2.28, p = 0.001) had increased hazard ratios for reoperation. The median period between the initial surgery and reoperation was 168.0 [Q1-Q3 84.0-407.8] days and negatively correlated with patient age at initial surgery (r = -0.199, p < 0.001).
The reoperation rate for presumed congenital SOP was 10.7%. Patients who underwent surgery on two or more vertical muscles or the superior oblique muscle had an increased risk of reoperation.
调查治疗先天性上斜肌麻痹(SOP)的手术类型和再手术率。
这是一项基于人群的回顾性队列研究,使用了美国的索赔数据。纳入了至少有 3 个月连续入组且初次手术后行斜视手术治疗先天性 SOP 的患者。我们调查了年龄、手术方法以及初次手术和再手术之间的时间间隔。使用 Cox 回归分析根据手术方法估计再手术的风险比。
共有 3998 例患者因先天性 SOP 接受手术治疗;2981 例(74.6%)仅行单一垂直肌(不包括上斜肌)手术。427 例(10.7%)患者行再手术。与仅行单侧单一垂直肌(不包括上斜肌)手术的患者相比,行上斜肌手术(单侧 2.08;95%CI,1.61-2.67,p<0.001;双侧 2.44;95%CI,1.40-4.28,p=0.002)和行两条或以上垂直肌(不包括上斜肌)手术(单侧 2.99;95%CI,2.00-4.49,p<0.001;双侧 1.68;95%CI,1.23-2.28,p=0.001)的患者再手术风险比更高。初次手术和再手术之间的中位时间为 168.0[Q1-Q3 84.0-407.8]天,与初次手术时患者的年龄呈负相关(r=-0.199,p<0.001)。
先天性 SOP 的再手术率为 10.7%。行两条或以上垂直肌或上斜肌手术的患者再手术风险增加。