通过底物的可见光直接激发实现的无光催化剂交叉脱氢偶联反应
The Photocatalyst-Free Cross-Dehydrogenative Coupling Reaction Enabled by Visible-Light Direct Excitation of Substrate.
作者信息
Guo Xuan, Shao Bing-Ru, Jiang Wen-Feng, Shi Lei
机构信息
School of Chemical Engineering, Dalian University of Technology, Dalian, 116024, P. R. China.
出版信息
J Org Chem. 2021 Nov 5;86(21):15743-15752. doi: 10.1021/acs.joc.1c01775. Epub 2021 Oct 25.
A new photocatalyst-free strategy for the cross-dehydrogenative C-C and C-P coupling reaction has been described. This protocol provides a concise method to synthesize various 1-substituted tetrahydroisoquinoline (THIQ) derivatives enabled by visible-light direct excitation of substrates without using any photocatalyst. Moreover, a wide substrate scope demonstrated good synthetic versatility and practicality.
一种用于交叉脱氢C-C和C-P偶联反应的新型无光催化剂策略已被报道。该方法提供了一种简洁的方法，可通过可见光直接激发底物来合成各种1-取代四氢异喹啉（THIQ）衍生物，而无需使用任何光催化剂。此外，广泛的底物范围显示出良好的合成通用性和实用性。
Zotero 插件