气腔转移和空气传播扩散——不同实体还是同一过程的不同表现？
Aerogenous Metastasis and Spread Through the Air Spaces - Distinct Entities or Spectrum of the Same Process?
机构信息
Division of Thoracic Imaging, Department of Medical Imaging, Ottawa Hospital Research Institute, University of Ottawa, 501 Smyth Road, Ottawa K1H 8M2, Canada.
Department of Pathology and Laboratory Medicine, Ottawa Hospital Research Institute, University of Ottawa, 501 Smyth Road, Ottawa K1H 8M2, Canada.
出版信息
Thorac Surg Clin. 2021 Nov;31(4):477-483. doi: 10.1016/j.thorsurg.2021.05.006.
Clinicopathological and imaging studies indicate that metastatic spread of cancer cells through the airways may occur in primary lung cancer. The term aerogenous metastasis was been proposed years before the concept of spread through the airspaces (STAS) was introduced in the current World Health Organization classification. The pathogenesis of STAS has not been fully elucidated. The current definition of STAS is controversial and limited to early stage adenocarcinomas. In this article, existing knowledge on the pathogenesis, histology, imaging findings, and clinical and prognostic significance of these 2 entities is presented.
临床病理和影像学研究表明，原发性肺癌中癌细胞可能通过气道发生转移。在目前的世界卫生组织分类中引入“通过气道播散”（STAS）这一概念之前，多年前就提出了“气源性转移”这一术语。STAS 的发病机制尚未完全阐明。目前 STAS 的定义存在争议，仅限于早期腺癌。本文介绍了这两种实体的发病机制、组织学、影像学表现以及临床和预后意义的现有知识。
Zotero 插件