Max Planck Institute for Brain Research, 60438 Frankfurt, Germany.
Institute for Physiology, Faculty of Medicine, University of Freiburg, 79108 Freiburg, Germany; Center for Basics in NeuroModulation (NeuroModul Basics), University of Freiburg, 79106 Freiburg, Germany.
Cell. 2021 Oct 28;184(22):5501-5503. doi: 10.1016/j.cell.2021.09.036.
Neuropeptides are the most diverse class of signaling molecules in the brain. Despite evidence for their involvement in several behavioral functions, the precise circuit elements and neuronal computations they control remain elusive. In this issue, Melzer et al. (2021) reveal how the neuropeptide GRP facilitates memory in the neocortex.
神经肽是大脑中种类最多的一类信号分子。尽管有证据表明它们参与了几种行为功能,但它们控制的确切电路元件和神经元计算仍然难以捉摸。在本期杂志中,Melzer 等人(2021 年)揭示了神经肽 GRP 如何促进新皮层的记忆。